Outcomes of Couples After Failed PGD Management: A Single-Center Study at the Paris PGD Center (Antoine Béclère - Necker)

Sponsor
Assistance Publique - Hôpitaux de Paris
Study ID
NCT07371312
Status
Recruiting
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Conditions

  • Infertility

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

Preimplantation genetic testing (PGT) is a reproductive genetic technique aimed at preventing the transmission of severe genetic disorders. In France, its use is strictly regulated and reserved for complex medical situations, often associated with challenging reproductive histories and significant psychological burden. Despite scientific advances, success rates in preimplantation genetic testing remain limited, making the care pathway a significant source of uncertainty regarding the future of the parental project.

Key Dates

First listed
Jan 27, 2026
Start date
Mar 25, 2026
Status verified
Apr 2026
Primary completion
Mar 25, 2028
Completion
Mar 25, 2028

Study Design

Enrollment
900 participants (estimated)

Primary Outcome Measure

Proportion of couples with at least one live-born child surviving ≥3 years after failure of preimplantation genetic diagnosis (PGD) [ Time Frame: At least 3 years after the failure of PGD care (date of last PGD-related medical procedure in the center) ]

Central Contacts

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