Chronic and Acute Cardiovascular Diseases in Elderly Intensive Care Patients

Sponsor
Heinrich-Heine University, Duesseldorf
Study ID
NCT07385482
Status
Not Yet Recruiting

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Conditions

  • Acute Cardiovascular Disease
  • Chronic Cardiovascular Disease
  • Frailty

Eligibility Criteria

Sex
ALL
Age
80 Years - N/A
Healthy Volunteers
Not accepted

Study Details

Very old patients are a rapidly growing and vulnerable population in acute cardiovascular care but remain underrepresented in clinical trials. Clinical outcomes in older intensive care unit (ICU) patients are determined less by chronological age than by their clinical phenotype, including cardiovascular comorbidities, frailty, polypharmacy, and functional and cognitive impairment. This prospective multicenter observational study aims to assess the impact of chronic and acute cardiovascular diseases on long-term outcomes and functional trajectories in older ICU patients. Using the international VIP research network, approximately 4,000 patients will be enrolled across different ICU specialties and healthcare systems and assessed multidimensionally using validated clinical scores. The study seeks to improve risk stratification and outcome prediction in older critically ill patients with cardiovascular disease and to address existing evidence gaps in acute cardiovascular and intensive care medicine.

Key Dates

First listed
Feb 4, 2026
Start date
Mar 1, 2026
Status verified
Jan 2026
Primary completion
Mar 1, 2026
Completion
Mar 1, 2027

Study Design

Enrollment
4,000 participants (estimated)

Primary Outcome Measure

mortality [ Time Frame: within 6 months ]

Central Contacts

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