MRI Evaluation of Spinal Cord Edema After CT-Guided Percutaneous Cordotomy in Cancer Pain Patients

Sponsor
Mersin University
Study ID
NCT07400055
Status
Not Yet Recruiting

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Conditions

  • Cancer Pain
  • Intractable Pain
  • Neuropathic Pain
  • Spinal Cord Edema

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • CT-guided Percutaneous Cervical Cordotomy — PROCEDURE
    Routine clinical percutaneous cervical cordotomy performed under CT guidance using radiofrequency ablation at the C1-C2 level for the treatment of intractable cancer pain.

Study Details

This observational study aims to evaluate changes in the spinal cord following CT-guided percutaneous cervical cordotomy performed for the treatment of intractable cancer-related pain. Cordotomy is a routine clinical procedure used to relieve severe pain in selected cancer patients. After the procedure, some patients may develop temporary neurological symptoms that are thought to be related to spinal cord edema. In this study, magnetic resonance imaging (MRI) will be performed as part of routine clinical follow-up on postoperative day 1 and at 1 month to assess the presence and extent of spinal cord edema. Clinical outcomes, including pain intensity and possible postprocedural symptoms, will be recorded and compared with MRI findings. The goal of this research is to better understand the relationship between imaging changes in the spinal cord and clinical outcomes after cordotomy, which may help improve patient care and postoperative management in the future.

Key Dates

First listed
Feb 10, 2026
Start date
Mar 1, 2026
Status verified
Feb 2026
Primary completion
Mar 1, 2027
Completion
Apr 1, 2027

Study Design

Enrollment
15 participants (estimated)

Arms

  • Arm: Percutaneous Cervical Cordotomy Cohort
    Adult patients with cancer-related pain undergoing routine CT-guided percutaneous cervical cordotomy and followed with postoperative MRI and clinical assessments.

Primary Outcome Measure

Presence and extent of spinal cord edema on cervical MRI after CT-guided percutaneous cordotomy [ Time Frame: Postoperative day 1 and 1 month ]

Central Contacts

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