OPEN-IPF: Observational Prediction modEl for cliNical Outcomes in Idiopathic Pulmonary Fibrosis

Sponsor
University of Modena and Reggio Emilia
Study ID
NCT07404423
Status
Not Yet Recruiting

Notify me when recruiting opens

Save your spot on the interest list for this study. We'll keep your details with this study so our team can follow up when recruiting opens.

Not yet recruiting

Add your contact details and location so we can keep your interest tied to this study.

Conditions

  • Idiopathic Pulmonary Fibrosis

Eligibility Criteria

Sex
ALL
Age
18 Years - 90 Years
Healthy Volunteers
Not accepted

Study Details

Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with marked inter-individual heterogeneity in trajectories and outcomes. Despite antifibrotic therapies, reliable risk stratification in routine practice remains suboptimal. OPEN-IPF is a multicentre retrospective observational cohort study designed to build a harmonised real-world dataset across Italian IPF referral centres to enable the development and external validation of machine-learning (ML) models predicting clinically relevant outcomes.

Key Dates

First listed
Feb 11, 2026
Start date
Jun 1, 2026
Status verified
Feb 2026
Primary completion
Jan 1, 2027
Completion
Jun 1, 2027

Study Design

Enrollment
1,000 participants (estimated)

Primary Outcome Measure

Disease progression (guideline-based functional/composite criteria) [ Time Frame: From baseline (index date) up to 12 months and up to end of available follow-up (maximum: 31 December 2025) ]

Central Contacts

Related Studies