Menopausal Impact of Opportunistic Salpingectomy for Ovarian Cancer Prevention

Sponsor
Umeå University
Study ID
NCT07423143
Status
Not Yet Recruiting

Notify me when recruiting opens

Save your spot on the interest list for this study. We'll keep your details with this study so our team can follow up when recruiting opens.

Not yet recruiting

Add your contact details and location so we can keep your interest tied to this study.

Conditions

Eligibility Criteria

Sex
FEMALE
Age
20 Years - 65 Years
Healthy Volunteers
Not accepted

Interventions

  • Opportunistic salpingectomy — PROCEDURE
    Removal of the fallopian tubes at the time of hysterectomy

Study Details

The goal of this clinical trial is to find out whether removing the fallopian tubes at the time of hysterectomy leads to an earlier menopause. The study includes women under 55 years of age who previously underwent hysterectomy as participants in the HOPPSA trial, where they were randomly assigned to either removal of the fallopian tubes or no removal. The main question is: • Does removing the fallopian tubes at the time of hysterectomy lead to an earlier menopause? Researchers will compare women who had their fallopian tubes removed during hysterectomy with women who had hysterectomy alone to see whether menopause occurs earlier after tube removal. Age at menopause will be estimated by measuring follicle-stimulating hormone (FSH) in small blood samples collected on a paper card. Participants will: * Collect 4-5 drops of blood using a finger prick * Place the drops on a paper card and mail it to the researchers * Complete an online questionnaire These steps will be done twice, one year apart.

Key Dates

First listed
Feb 20, 2026
Start date
Mar 31, 2026
Status verified
Feb 2026
Primary completion
Feb 28, 2029
Completion
Dec 31, 2057

Study Design

Enrollment
2,100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Opportunistic salpingectomy
    Salpingectomy at the time of hysterectomy for a benign reason
  • No Intervention: No salpingectomy
    No salpingectomy at hysterectomy for a benign reason

Primary Outcome Measure

Age at menopause [ Time Frame: 1 year ]

Central Contacts

Find similar trials

Nationwide
Menopause trialsWomen's health trialsFertility trials

Related Studies