Chronic Kidney Disease Associated Diet

Sponsor
Recep Tayyip Erdogan University Training and Research Hospital
Study ID
NCT07427069
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Study Details

The goal of this observational study is to investigate the relationship between chronic kidney disease (CKD) and periodontitis, and to evaluate the potential mediating role of dietary inflammatory potential, measured by the Dietary Inflammatory Index (DII), in this association. The main question it aims to answer is: Does a pro-inflammatory diet, as reflected by a higher DII score, exacerbate periodontal inflammation in individuals with chronic kidney disease? Participants will include adults diagnosed with CKD at various stages. Periodontal status will be assessed through clinical parameters such as probing depth, clinical attachment loss, and bleeding on probing. Dietary intake will be evaluated using a validated food frequency questionnaire, and DII scores will be calculated accordingly. The study will aim to observe and analyze whether dietary inflammation contributes to increased periodontal disease severity in CKD patients, potentially offering insight into modifiable risk factors relevant to both systemic and oral health.

Key Dates

First listed
Feb 23, 2026
Start date
Apr 20, 2026
Status verified
Feb 2026
Primary completion
Oct 19, 2026
Completion
Nov 16, 2026

Study Design

Enrollment
100 participants (estimated)

Arms

  • Arm: Patients diagnosed with chronic kidney disease
    Chronic kidney disease is diagnosed if the eGFR is below 60 ml/min/1.73 m2 for at least 3 months or if the urine albumin-creatinine ratio is above 30 mg/g (proteinuria).

Primary Outcome Measure

Dietary Inflammatory Index [ Time Frame: Day 1 ]

Central Contacts

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