Nephrology Clinical Trials

Recruiting nephrology studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat nephrology. Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting nephrology studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting nephrology trials

Within

MRI Technical Development and Applications in Kidney Disease

for Chronic Kidney Diseases

1 site in Minneapolis

Sponsor: University of Minnesota

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT02421497

Veteran Centered Meal Intervention in Chronic Kidney Disease

for Chronic Kidney Disease

1 site in Aurora

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80

Code: NCT07793591

Breakthrough - T1DM and Chronic Kidney Disease

for Diabete Type 1

2 sites incl. Miami

Sponsor: University of Chicago

Sex: All·Age: 18 - 70

Code: NCT07592000·Phase 1, Phase 2

Apply to this trial

Finerenone for AKI: a Multicenter, Randomized, Placebo-Controlled Feasibility Pilot Trial

for Acute Kidney Injury

Sponsor: Jean-Maxime Côté

Sex: All·Age: 18+

Code: NCT07775482

Hybrid Dissemination Study of A Digital-Analog Intervention to Increase Live Donor Kidney Transplantation

for End-Stage Renal Disease

1 site in Buffalo

Sponsor: State University of New York at Buffalo

Sex: All·Age: 18+

Code: NCT07072767

Prediction and Prevention of Bloodstream Infections After Kidney Transplantation

for Kidney Transplant Infection

Sponsor: Susanne Dam Nielsen, MD, DMSc

Sex: All·Age: 18+

Code: NCT07407673·Phase 3

NRP + ex Situ HMPO2 vs NRP Alone in DCD Kidney Transplantation

for Kidney Transplant

Sponsor: Karolinska University Hospital

Sex: All·Age: 18+

Code: NCT07779187

Doppler Evaluation for Congestive Acute Kidney Injury in Critical Illness

for Acute Kidney Injury

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT07291778

Antibiotics for Kidney Transplant Recipients

for Kidney Transplant

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: Up to 29

Code: NCT07106125·Phase 4

(TNX-1500) in Kidney Transplant Recipients

for Kidney Transplant

2 sites in Boston

Sponsor: Ayman Al Jurdi, MD

Sex: All·Age: 18 - 75

Code: NCT07204080·Phase 2

BicMag Study - Improving Mineral Buffering Capacity in Dialysis Patients

for End Stage Renal Disease

Sponsor: Elisabethinen Hospital

Sex: All·Age: 18+

Code: NCT07663279

Placental Cells for Diabetic Foot Ulcers

for Diabetic Foot Ulcer

1 site in Winston-Salem

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT07686094·Phase 1

Food As Medicine to Reduce CKD Burden in Health Disparity Populations

for Chronic Kidney Disease

2 sites in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT07759401

Real-Time Acute Kidney Injury Perioperative Prediction Clinical Trial

for Acute Kidney Injury

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07604662

A Prospective, Observational Study to Evaluate the Safety and Feasibility of Continuous Renal Replacement Therapy With Regional Citrate Anticoagulation in a Cohort Critical Ill Patients With Acute Kidney Injury and Presumed Absent Citrate Metabolism

for Acute Kidney Injury

Sponsor: University Hospital, Antwerp

Sex: All·Age: 18+

Code: NCT07751874

Amino Acid Infusion in Cardiac Surgery

for Acute Kidney Injury

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT07030933·Phase 4

Nicotinamide Riboside Supplementation in Chronic Kidney Disease

for Chronic Kidney Disease

1 site in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 30+

Code: NCT07693543·Phase 2

Treatment Costs of Kidney Injury in Patients Having Heart Surgery in the UK

for Acute Kidney Injury

Sponsor: The Royal Wolverhampton Hospitals NHS Trust

Sex: All·Age: 18+

Code: NCT07719569

Erector Spinae Oxygen Saturation and AKI After OPCAB

for Acute Kidney Injury

Sponsor: Yonsei University

Sex: All·Age: 19+

Code: NCT07760129

Ultrasound Evaluation of Fluid Tolerance and Fluid Responsiveness in Postoperative Cardiac Surgery Patients

for Cardiac Surgical Procedures

Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

Sex: All·Age: 18+

Code: NCT07792707

Targeted Nutritional Management for Children With Chronic Kidney Disease

for Chronic Kidney Disease

Sponsor: Assiut University

Sex: All·Age: 6 Months - 12

Code: NCT07795190

Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System in the Healing of Diabetic Foot Ulcers

for Diabetic Foot Ulcer

Sponsor: Syntr Health Technologies, Inc.

Sex: All·Age: 18 - 85

Code: NCT05519501

Development and Test of a Communication Skills Training for Transplant Providers - Aims 2 & 3

for Kidney Disease, Chronic

2 sites incl. Livingston

Sponsor: Temple University

Sex: All·Age: 18 - 80

Code: NCT06182475

Effect of Empagliflozin in Patients With eGFR Between 10 and 20 ml/Min/1.73m2

for Chronic Kidney Diseases

Sponsor: Centre Hospitalier Universitaire de Nice

Sex: All·Age: 18 - 80

Code: NCT07074418·Phase 4

Handgrip Exercise Training and CKD

for Chronic Kidney Diseases

1 site in Atlanta

Sponsor: Emory University

Sex: All·Age: 45 - 85

Code: NCT07094906

Mitigating DKA in Type 1 Diabetes for Safe Use of SGLT Inhibitors Using Dual Continuous Ketone and Glucose Monitoring.

for Type 1 Diabetes Mellitus

1 site in Minneapolis

Sponsor: HealthPartners Institute

Sex: All·Age: 18 - 75

Code: NCT07325201·Phase 2

Pragmatic Trial of Messaging to Providers About Treatment of Chronic Kidney Disease

for Chronic Kidney Diseases

1 site in New Haven

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT07430930

Letermovir for R+ Study

for Kidney Transplant

1 site in Madison

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+

Code: NCT07706166·Phase 4

Cemiplimab for Kidney Transplant Recipients With Advanced Cutaneous Squamous Cell Carcinoma

for Kidney Transplant Recipient

1 site in St Louis

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT07715734·Phase 2

Investigating Vascular Properties of HEMI and SPG Signals in Individuals With or at Risk for Chronic Kidney Disease

for Chronic Kidney Disease

Sponsor: Institut National de la Santé Et de la Recherche Médicale, France

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07604922

A Study to Evaluate the Impact of Renal Impairment on the Pharmacokinetics (PK) of Ribupatide

for End Stage Renal Disease

Sponsor: Kailera

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT07793929·Phase 1

Early Biomarker Kidney Injury Assessment After Acumen Directed Fluid Management in Cardiac Surgery

for Renal Injury

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06109714

Impact of Culture of Perfusion Fluid on Donor-derived Infection Management and Outcome in Liver and Kidney Transplant

for Liver Transplant Infection

Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna

Sex: All·Age: 18+

Code: NCT07651137

Terbinafine for CSA-AKI Prevention

for Acute Kidney Injury

Sponsor: Guangdong Provincial People's Hospital

Sex: All·Age: 18 - 75

Code: NCT07738328·Phase 2

NAD Supplementation to Reduce the Incidence of Cardiac Surgery Associated Acute Kidney Injury

for Acute Kidney Injury

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT07739290

The Effect of L-Carnitine on Wound Healing in Patients With Diabetic Foot Ulcer.

for Diabetic Foot Ulcer

Sponsor: Ain Shams University

Sex: All·Age: 30 - 75

Code: NCT07768228·Phase 2

Apply to this trial

Optimization of Therapeutic Drug Monitoring in Pediatric Kidney Transplant

for Kidney Transplant

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 1+

Code: NCT07769567

Negative Pressure Wound Therapy Devices in Total Knee Arthroplasty

for Wound Surgical

Sponsor: The Cleveland Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07770633

RAndomized EHR-based Prescribing to Improve Disease-modifying Therapies for Cardio-Kidney-Metabolic Care (RAPID-CKM)

for Chronic Kidney Disease

2 sites incl. Dallas

Sponsor: Baylor Research Institute

Sex: All·Age: 18+

Code: NCT07605390

Designing and Implementing a Safety Net Surveillance Program for High Risk CKD

for Chronic Kidney Diseases

Sponsor: University of Manitoba

Sex: All·Age: 18+

Code: NCT07724288

A Prompt REstart Study of Renin-Angiotensin System Inhibitors After Acute Kidney Injury

for Acute Kidney Injury

1 site in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT07734636·Phase 4

ProNephro NGAL Test for Early Detection of Acute Kidney Injury in Adult ICU Patients (ALPACA)

for Acute Kidney Injury

Sponsor: BioPorto Diagnostics

Sex: All·Age: 22+

Code: NCT07751913

Performance and Safety of Mepilex® Up in Leg and Foot Ulcers and Skin Tears

for Leg Ulcer

Sponsor: Molnlycke Health Care AB

Sex: All·Age: 18+

Code: NCT07782008

A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.

for Chronic Kidney Disease

33 sites incl. Sheffield

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07753993·Phase 3

Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis

for End Stage Renal Disease

1 site in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 25 - 74

Code: NCT06609343·Phase 1, Phase 2

Sarcopenia in Chronic Kidney Disease (CKD) Patients

for Chronic Kidney Disease

1 site in San Antonio

Sponsor: The University of Texas Health Science Center at San Antonio

Sex: All·Age: 45 - 75

Code: NCT07437053·EARLY_Phase 1

Safety and Tolerability of IDO-1 Inhibition in the Prevention of EBV-related Pathology in EBV Negative Kidney Transplant Recipients Receiving an Organ From EBV Positive Donors

for EBV Infections

Sponsor: University Hospital, Basel, Switzerland

Sex: All·Age: 18+

Code: NCT07368153·Phase 2

Apply to this trial

The Vancomycin Piperacillin/Tazobactam (VPT) Patient Safety Trial (VPS)

for Infection

3 sites incl. Cooperstown

Sponsor: Bassett Healthcare

Sex: All·Age: 18+

Code: NCT07556107·Phase 4

Apply to this trial

Pharmacokinetics of Zoledronic Acid in Patients on Dialysis

for Chronic Kidney Disease

Sponsor: University of Campinas, Brazil

Sex: All·Age: 18+

Code: NCT07741136·Phase 1

Clinical Characteristics and In-Hospital Outcomes of Critically Ill Patients Receiving Hemodialysis or Continuous Venovenous Hemodiafiltration in the Emergency Department

for Acute Kidney Injury

Sponsor: Antalya Health Sciences University

Sex: All·Age: 18+

Code: NCT07765030

Subcutaneous Dexpanthenol Administration and Wound Epithelialization

for Chronic Wounds

Sponsor: Dilara CANBAY OZDEMIR

Sex: All·Age: 18+

Code: NCT07395674

The NTU JO-SMART Study

for Knee Osteoarthristis

Sponsor: National Taiwan University Hospital

Sex: All·Age: 18 - 75

Code: NCT07317310

Apply to this trial

4-7-8 Breathing for Fatigue and Sleep Management in Hemodialysis

for Chronic Kidney Diseases

Sponsor: Izmir Kavram Vocational School

Sex: All·Age: 18 - 85

Code: NCT07700693

Early Kidney Injury Biomarkers in Gynecologic Laparoscopic Surgery

for Acute Kidney Injury

Sponsor: Medipol University

Sex: Female·Age: 18+

Code: NCT07704242

Renal Efficacy and Safety of the Novel Oral Small-Molecule GLP-1RA HRS-7535 Evaluated in Participants With Chronic Kidney Disease

for Chronic Kidney Disease

Sponsor: Shandong Suncadia Medicine Co., Ltd.

Sex: All·Age: 18+

Code: NCT07625774·Phase 3

Effectiveness of Subgingival Instrumentation on Delaying End-stage Renal Disease Among Chronic Kidney Disease Patients

for Chronic Kidney Disease

Sponsor: Postgraduate Institute of Dental Sciences Rohtak

Sex: All·Age: 40 - 70

Code: NCT07635797

Analysis of Continuous Kidney Replacement Therapy (CKRT) Treatments With multiFlux Hemofilters Using Regional Citrate Anticoagulation (RCA) or Systemic Heparin Anticoagulation

for Acute Kidney Injury

Sponsor: Fresenius Medical Care Deutschland GmbH

Sex: All·Age: 1+

Code: NCT07679568

Remote vs In-Person Prehabilitation for Kidney Transplant Candidates

for Chronic Kidney Disease (CKD)

Sponsor: Hospital Clinic of Barcelona

Sex: All·Age: 18+

Code: NCT07701382

Immunosuppression Optimization Using The Prospera Assay In Kidney Transplant Recipients (IMPAKT)

for Kidney Transplant

Sponsor: Natera, Inc.

Sex: All·Age: 18+

Code: NCT07718633

A Study to Learn About How a New Nurandociguat Tablet is Absorbed and Processed in the Body Compared to an Old Tablet and How Food Affects the Way the New Tablet is Absorbed and Processed in the Body

for Chronic Kidney Disease

Sponsor: Bayer

Sex: All·Age: 18 - 58·Accepts healthy volunteers

Code: NCT07722585·Phase 1

Apply to this trial

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Nephrology clinical trials — common questions

Are nephrology clinical trials free to join?

Yes. Participating in a nephrology clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a nephrology clinical trial?

Each nephrology study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a nephrology trial near me?

Use the location controls above. We'll show recruiting nephrology trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many nephrology trials are recruiting right now?

We're currently tracking roughly 229 recruiting nephrology trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Nephrology trials by city

Birmingham, AL Boston, MA Los Angeles, CA Aurora, CO San Francisco, CA Chicago, IL Jacksonville, FL Miami, FL Cincinnati, OH Palo Alto, CA Sacramento, CA San Diego, CA

Conditions in this area

Chronic kidney disease End-stage renal disease Acute kidney injury Kidney transplant Diabetic foot ulcer