Effects of Gesture Plus Verbal Treatment (GVT) in Cantonese Speakers With Aphasia

Sponsor
Hong Kong University
Study ID
NCT07455162
Status
Recruiting
Apply to this trial

Conditions

  • Aphasia
  • Gestures

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Verbal treatment — BEHAVIORAL
    This study will involve the following naming interventions: 1) Semantic Features Analysis, 2) Modified Ortho-phonological cueing therapy and Phonological Component Analysis, and 3) Repetition with Cueing Hierarchy.
  • Gesture plus verbal treatment — BEHAVIORAL
    This study will involve the following interventions: 1\) Combined Semantic and Gesture treatment, 2) Combined Phonological and Gesture treatment, and 3) Combined Repetition and Gesture treatment.

Study Details

This research aims to explore the relative efficacy of Verbal-only and GVT on naming difficulty in Cantonese-speaking people with aphasia (PWA). The primary research question in this study is: "For Cantonese-speaking people with aphasia, what are the relative effects of verbal treatment compared to gesture plus verbal treatment (GVT) on verbal and gesture naming at different levels?" People with aphasia will be engaged in a repeated measures experimental design. Participants will be engaged in two phases of training. In the first phase, participants will be assigned to receive verbal-only treatment. To minimize and prevent the carry-over effects caused by the first intervention, a one-month washout period will be implemented before the start of the second phase. After a washout period, participants will switch to GVT in the second phase.

Key Dates

First listed
Mar 6, 2026
Start date
Apr 1, 2025
Status verified
Feb 2026
Primary completion
Sep 30, 2028
Completion
Sep 30, 2028

Study Design

Enrollment
90 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Verbal-only
    This is a within-subject comparison study where each participant receives both interventions sequentially. During the first phase, participants receive verbal-only therapy (VT). In the subsequent phase, they receive Gesture verbal treatment (GVT). The order of interventions is fixed, and each participant acts as their own control to compare the effects of the two interventions.
  • Active Comparator: Gesture plus Verbal
    This is a within-subject comparison study where each participant receives both interventions sequentially. During the first phase, participants receive verbal-only therapy (VT). In the subsequent phase, they receive Gesture verbal treatment (GVT). The order of interventions is fixed, and each participant acts as their own control to compare the effects of the two interventions.

Primary Outcome Measure

Changes in the scores of the Naming Probes [ Time Frame: From enrollment to the end of treatment at 4 weeks ]

Central Contacts

Related Studies