Observational Clinical Study on the Association Between Lactate-mediated Gut Microbiota Alterations and Disease Progression in Liver Cirrhosis.

Sponsor
Zhujiang Hospital
Study ID
NCT07455175
Status
Not Yet Recruiting

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Conditions

  • Cirrhosis

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Accepted

Interventions

  • observational study, no intervention — OTHER
    observational study, no intervention

Study Details

To investigate the association between lactate-mediated alterations in the gut microbiota and disease progression in patients with liver cirrhosis; and to examine the correlations of lactate levels among serum, fecal, and tissue samples in patients with liver cirrhosis.

Key Dates

First listed
Mar 6, 2026
Start date
Apr 1, 2026
Status verified
Feb 2026
Primary completion
Oct 1, 2028
Completion
Oct 1, 2028

Study Design

Enrollment
200 participants (estimated)

Arms

  • Arm: Cirrhosis
  • Arm: Healthy control

Primary Outcome Measure

Gut microbiota composition [ Time Frame: baseline ]

Central Contacts

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