Retinal Oxygen Metabolism in Children With Myopia

Sponsor
Medical University of Vienna
Study ID
NCT07473401
Status
Not Yet Recruiting

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Conditions

  • Myopia

Eligibility Criteria

Sex
ALL
Age
8 Years - 13 Years
Healthy Volunteers
Accepted

Study Details

The aim of the present study is to gain more information about retinal functional parameters in myopic children in Europe. For this purpose, a prospective case-control study in children aged between 8 and 13 years, as this is the usual age of myopia onset, will be conducted. Forty myopic children will be age- and sex-matched to non-myopic controls. Retinal oxygen extraction will be used as the main outcome parameter, as data from animal and human studies point towards an involvement of hypoxia in the disease process. In addition, other parameters probably linked to myopia will be investigated, such as retinal and choroidal blood flow as well as choroidal and retinal vessel density and anatomical structures such as choroidal and central retinal thickness. Also, questionnaires about lifestyle factors will be completed.

Key Dates

First listed
Mar 16, 2026
Start date
May 11, 2026
Status verified
Mar 2026
Primary completion
Jan 2, 2027
Completion
Jan 2, 2027

Study Design

Enrollment
80 participants (estimated)

Arms

  • Arm: children with myopia
    children with myopia
  • Arm: healthy age- and sex-matched controls
    healthy age- and sex-matched controls

Primary Outcome Measure

Retinal oxygen extraction [ Time Frame: Study Day 1 ]

Central Contacts

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