Associations Between Dietary Patterns, LDL Aggregation, and Cardiometabolic Health: A Cross-sectional Analysis.

Sponsor
Liverpool John Moores University
Study ID
NCT07474233
Status
Not Yet Recruiting

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Conditions

  • Atherosclerosis Cardiovascular Disease
  • Dyslipidaemia
  • Endothelial Dysfunction
  • Metabolic Syndrome

Eligibility Criteria

Sex
ALL
Age
25 Years - 60 Years
Healthy Volunteers
Accepted

Study Details

This study aims to investigate the extent to which vegan or plant-based, omnivorous, and carnivore dietary patterns affect LDL aggregation susceptibility (the affinity for LDL cholesterol particles to clump together in the blood), which may promote plaque build-up in arteries. Using a cross-sectional mixed-methods design, the study will measure LDL aggregation, blood lipids, and other metabolic biomarkers in individuals following these diets, and combine these data with dietary and behavioural information to examine links with cardiovascular and metabolic health.

Key Dates

First listed
Mar 16, 2026
Start date
May 31, 2026
Status verified
Mar 2026
Primary completion
May 31, 2027
Completion
May 31, 2027

Study Design

Enrollment
90 participants (estimated)

Arms

  • Arm: Vegan or plant-based diet
    Individuals who identify as adhering to a vegan or plant-based diet habitually for a minimum period of six months.
  • Arm: Carnivore diet
    Individuals who identify as adhering to a carnivore diet composed exclusively of animal-based products habitually for a minimum period of six months.
  • Arm: Omnivore diet
    Individuals who identify as adhering to an omnivorous (animal and plant-based) diet habitually for a minimum period of six months.

Primary Outcome Measure

LDL aggregation susceptibility [ Time Frame: Baseline upon enrollment. ]

Central Contacts

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