A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia

Part of paid clinical trials in Sunrise, Florida.

Sponsor
Regeneron Pharmaceuticals
Study ID
NCT07477704
Phase
PHASE2
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

Study Details

This study is researching an experimental drug called alirocumab, referred to as "study drug". In the United States, alirocumab is approved for the treatment of hypercholesterolemia (high blood cholesterol levels). The aim of the study is to see how safe and effective alirocumab is when given weekly to adult participants who have hypercholesterolemia. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug once a week * How much study drug is in the blood at different times

Key Dates

Start date
Jun 29, 2026
Status verified
Jun 2026
Primary completion
Dec 29, 2026
Completion
Feb 23, 2027

Study Design

Enrollment
420 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Arm 1 - Low Dose
  • Experimental: Arm 2 - Medium Dose
  • Experimental: Arm 3 - High Dose
  • Experimental: Arm 4 - Control Dose

Primary Outcome Measure

Percent change in LDL-C [ Time Frame: From Baseline through Week 12 ]

Central Contacts

Locations (6)

FacilityCityStateZIPSite coordinators
Precision Clinical ResearchSunriseFlorida33351-
Balanced Life Health Care SolutionsLawrencevilleGeorgia30046-
Mercury Street Medical Group, PLLCButteMontana59701-
Velocity Clinical Research - DurhamDurhamNorth Carolina27701-
Velocity Clinical Research, MedfordMedfordOregon97504-
Velocity Clinical Research DallasDallasTexas75230-

Find similar trials in Sunrise, FL

By research site
Precision Clinical Research· Sunrise, FLBalanced Life Health Care Solutions· Lawrenceville, GAMercury Street Medical Group, PLLC· Butte, MTVelocity Clinical Research - Durham· Durham, NCVelocity Clinical Research, Medford· Medford, ORVelocity Clinical Research Dallas· Dallas, TX

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