A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia

Part of paid clinical trials in Anniston, Alabama.

Sponsor
Regeneron Pharmaceuticals
Study ID
NCT07477704
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

Study Details

This study is researching an experimental drug called alirocumab, referred to as "study drug". In the United States, alirocumab is approved for the treatment of hypercholesterolemia (high blood cholesterol levels). The aim of the study is to see how safe and effective alirocumab is when given weekly to adult participants who have hypercholesterolemia. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug once a week * How much study drug is in the blood at different times

Key Dates

First listed
Mar 17, 2026
Start date
Jun 17, 2026
Status verified
Jul 2026
Primary completion
Dec 29, 2026
Completion
Feb 23, 2027

Study Design

Enrollment
420 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Arm 1 - Low Dose
  • Experimental: Arm 2 - Medium Dose
  • Experimental: Arm 3 - High Dose
  • Experimental: Arm 4 - Control Dose

Primary Outcome Measure

Percent change in LDL-C [ Time Frame: From Baseline through Week 12 ]

Central Contacts

Locations (34)

FacilityCityStateZIPSite coordinators
Pinnacle Research GroupAnnistonAlabama36207-
Cullman Clinical TrialsCullmanAlabama35055-
Anaheim Clinical TrialsAnaheimCalifornia92801-
Cenexel CNSLos AlamitosCalifornia90720-
Diablo Clinical Research - Flourish ResearchWalnut CreekCalifornia94598-
Tampa Bay Medical ResearchClearwaterFlorida33761-
Southwest General Healthcare CenterFort MyersFlorida33907-
Precision Clinical ResearchSunriseFlorida33351-
K2 Medical Research The VillagesThe VillagesFlorida32159-
Center for Advanced Research and EducationGainesvilleGeorgia30501-
Balanced Life Health Care SolutionsLawrencevilleGeorgia30046-
East-West Medical Research InstituteHonoluluHawaii96814-
L-MARC Research CenterLouisvilleKentucky40213-
Tandem Clinical ResearchMarreroLouisiana70072-
Mercury Street Medical Group, PLLCButteMontana59701-
Velocity Clinical Research - OmahaOmahaNebraska68134-
Palm Research Center, Mountainview Medical CenterLas VegasNevada89128-
Velocity Clinical Research - DurhamDurhamNorth Carolina27701-
Accellacare of WilmingtonWilmingtonNorth Carolina28401-
Ohio Clinical TrialsColumbusOhio43212-
AMR NormanNormanOklahoma73069-
Lynn Health Science InstituteOklahoma CityOklahoma73112-
Velocity Clinical Research, MedfordMedfordOregon97504-
Altoona Center for Clinical ResearchDuncansvillePennsylvania16635-
Tribe Clinical ResearchGreenvilleSouth Carolina29607-
Coastal Carolina Research Center_North CharlestonNorth CharlestonSouth Carolina29405-
Velocity Clinical Research DallasDallasTexas75230-
Valley Institute of Research, Rockwood Medical ClinicFort WorthTexas76164-
Be Well Clinical Studies - Round RockRound RockTexas78681-
Endeavor Clinical TrialsSan AntonioTexas78240-
Flourish Research - San Antonio Medical TrialsSan AntonioTexas78229-
Consano Clinical Research, LLCShavano ParkTexas78231-
Charlottesville Medical ResearchCharlottesvilleVirginia22911-
Rainier Clinical Research CenterRentonWashington98057-

Find similar trials in Anniston, AL

By research site
Pinnacle Research Group· Anniston, ALCullman Clinical Trials· Cullman, ALAnaheim Clinical Trials· Anaheim, CACenexel CNS· Los Alamitos, CADiablo Clinical Research - Flourish Research· Walnut Creek, CATampa Bay Medical Research· Clearwater, FL

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