Valsalva SBP Drop and LVOT Obstruction

Sponsor
Shanghai Zhongshan Hospital
Study ID
NCT07483125
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • participants are not assigned an intervention as part of the study — OTHER
    participants are not assigned an intervention as part of the study

Study Details

This study aimed to evaluate the efficacy of non-invasive dynamic blood pressure monitoring in assessing left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy. We prospectively collected SBP waveforms and LVOT gradient data from patients with obstructive and non-obstructive disease, systematically analyzed their correlation, and explored its clinical value in different clinical scenarios.

Key Dates

Start date
Dec 1, 2025
Status verified
Mar 2026
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
800 participants (estimated)

Arms

  • Arm: HCM
    HCM patients

Primary Outcome Measure

Sensitivity and specificity of SBP waveform in differentiating obstructive HCM caused by left ventricular outflow tract obstruction [ Time Frame: 1 year ]

Central Contacts