Glucose Profiles in Women With Polycystic Ovary Syndrome

Sponsor
Centre Hospitalier Universitaire, Amiens
Study ID
NCT07483723
Status
Recruiting
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Conditions

  • Continuous Glucose Monitoring
  • Glucose Profile
  • Insulin Resistance
  • Polycystic Ovary Syndrome

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • sensor — DEVICE
    Free-style-libre pro sensor application for 14 days
  • Age reader — DEVICE
    Analysis of glycation end products by AGE reader

Study Details

Polycystic ovary syndrome is a very common condition that is associated with metabolic complications. Patients with polycystic ovary syndrome exhibit insulin resistance and are at greater risk to develop type 2 diabetes. This syndrome is heterogeneous, classified according to 4 phenotypes (A-D). It seems that certain phenotypes are less exposed to insulin resistance and metabolic complications. However, only a few studies have evaluated the glucose profile according to phenotype. New technologies now make it possible to monitor glucose levels continuously. The aim of this project is to evaluate glucose profile parameters using continuous glucose monitoring, and to compare these profiles according to different PCOS phenotypes.

Key Dates

First listed
Mar 19, 2026
Start date
Jan 6, 2026
Status verified
Mar 2026
Primary completion
Jul 31, 2027
Completion
Jul 31, 2027

Study Design

Enrollment
80 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Phenotype A
    oligomenorrhoea or amenorrhoea + hyperandrogenism + polycystic ovary morphology or elevated AMH levels
  • Experimental: Phenotype B
    hyperandrogenism + oligomenorrhoea or amenorrhoea
  • Experimental: Phenotype C
    hyperandrogenism + polycystic ovary morphology or elevated AMH levels
  • Experimental: Phenotype D
    oligomenorrhoea or amenorrhoea + polycystic ovary morphology or elevated AMH levels

Primary Outcome Measure

Time in range (TIR) [ Time Frame: 14 days ]

Central Contacts

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