G8 Screening Tool Validation in Older Adults With Cancer in Portugal

Sponsor
Hospital de Braga
Study ID
NCT07487298
Status
Not Yet Recruiting

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Conditions

  • Aged
  • Cancer
  • Frailty

Eligibility Criteria

Sex
ALL
Age
70 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • G8 Screening Tool — OTHER
    The G8 is a screening tool used to identify frailty in older patients with cancer and to select those who may benefit from a comprehensive geriatric assessment.
  • Comprehensive Geriatric Assessment — OTHER
    A multidimensional diagnostic process used to evaluate frailty across multiple domains including functional, cognitive, nutritional, and social status.

Study Details

The G8 screening tool is widely recommended for the identification of frailty in older adults with cancer. However, prospective validation data in the Portuguese population are currently lacking. This prospective observational study aims to evaluate the diagnostic performance of the G8 screening tool compared with a Comprehensive Geriatric Assessment (CGA) in older adults with cancer. Patients aged ≥70 years with solid tumors will be assessed using both the G8 screening tool and a multidimensional CGA. Frailty will be defined as impairment in at least one CGA domain. The performance of the G8 will be evaluated in terms of sensitivity, specificity, and area under the receiver operating characteristic curve. This study aims to provide the first prospective validation of the G8 screening tool in Portuguese older adults with cancer and to support its implementation in clinical practice.

Key Dates

First listed
Mar 23, 2026
Start date
Mar 20, 2026
Status verified
Mar 2026
Primary completion
Jun 30, 2027
Completion
Dec 15, 2027

Study Design

Enrollment
150 participants (estimated)

Arms

  • Arm: Older Adults With Cancer
    Patients aged ≥70 years with a diagnosis of cancer undergoing geriatric assessment, including G8 screening and comprehensive geriatric assessment.

Primary Outcome Measure

Diagnostic Accuracy of the G8 Screening Tool for Detecting Frailty [ Time Frame: At baseline (single assessment at study inclusion) ]

Central Contacts

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