Anderson-Fabry Disease Fitness Improvement Training: A-FAD-FIT

Sponsor
General University Hospital, Prague
Study ID
NCT07495410
Status
Enrolling By Invitation

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Physiotherapy exercise programe — BEHAVIORAL
    A 12-week physiotherapy and exercise program consisting of 45-minute sessions performed three times per week and gradual increase in daily step count by approximately 10 percent every 2 weeks. The intervention combines aerobic and strengthening components, including body weight exercises and resistance band training, together with counting of daily steps. Adherence is monitored using exercise diaries and regular follow-up during therapy sessions.

Study Details

This study will evaluate whether a 12-week physiotherapy and exercise program can improve physical function and quality of life in patients with Anderson-Fabry disease. Participants will complete assessments before and after the program. The intervention includes regular exercise sessions using body weight, resistance bands, and gradual increases in daily physical activity. The study is intended to determine whether a structured physiotherapy program is feasible and potentially beneficial for people living with Anderson-Fabry disease.

Key Dates

Start date
Oct 6, 2025
Status verified
Mar 2026
Primary completion
Dec 31, 2027
Completion
Jun 30, 2028

Study Design

Enrollment
15 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Physiotherapy intervention
    Participants will receive a 12-week targeted physiotherapy and exercise intervention consisting of 45-minute sessions performed three times per week and increasing number of daily steps. The program combines aerobic and strengthening exercise, including body weight exercises, resistance band training, and a gradual increase in daily step count.

Primary Outcome Measure

Change in cardiorespiratory fitness [ Time Frame: Baseline and after 12 weeks ]

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