Assessing the Association Between H. Pylori Persistence and the Severity of Insulin Resistance in Patients With Metabolic Syndrome

Sponsor
Center of New Medical Technologies
Study ID
NCT07501858
Status
Recruiting
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Conditions

  • Metabolic Syndrome

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Not accepted

Study Details

This retrospective cohort study evaluates the association between H. pylori persistence and insulin resistance severity (HOMA-IR) in 100 patients with metabolic syndrome at Novosibirsk's Center for New Medical Technologies (CNMT). Patients are divided into infected (n=50) and non-infected (n=50) groups, assessing metabolic parameters, gastro panel, and CRP. Primary endpoint: HOMA-IR differences; secondary: correlations with gastric inflammation and metabolic markers.

Key Dates

First listed
Mar 30, 2026
Start date
Apr 1, 2026
Status verified
Mar 2026
Primary completion
Apr 1, 2028
Completion
Jul 1, 2028

Study Design

Enrollment
100 participants (estimated)

Arms

  • Arm: group with persistence of H. pylori
    group with metabolic syndrome and persistence of H. pylori
  • Arm: group without persistence of H. pylori
    group without metabolic syndrome and persistence of H. pylori

Primary Outcome Measure

Difference in HOMA-IR index between H. pylori-positive and -negative patients. [ Time Frame: No more than 2 days after inclusion in the study ]

Central Contacts

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