The Role of Urinary RhoA, NGF, and BDNF Levels in Overactive Bladder and Vitamin D Deficiency

Sponsor
Tarik Emre Sener
Study ID
NCT07513363
Status
Not Yet Recruiting

Notify me when recruiting opens

Save your spot on the interest list for this study. We'll keep your details with this study so our team can follow up when recruiting opens.

Not yet recruiting

Add your contact details and location so we can keep your interest tied to this study.

Conditions

  • Overactive Bladder
  • Vitamin D Deficiency

Eligibility Criteria

Sex
ALL
Age
N/A - 18 Years
Healthy Volunteers
Accepted

Interventions

  • Urotherapy — BEHAVIORAL
    Diagnosis and first-line treatment (urotherapy) will be conducted per European Association of Urology (EAU) guidelines.

Study Details

The primary aim of this study is to evaluate the role of three specific urinary proteins-RhoA, Nerve Growth Factor (NGF), and Brain-Derived Neurotrophic Factor (BDNF)-as potential biomarkers for the diagnosis and follow-up of children aged 4-18 diagnosed with Overactive Bladder (OAB) and Vitamin D deficiency.

Key Dates

First listed
Apr 7, 2026
Start date
May 1, 2026
Status verified
Apr 2026
Primary completion
Dec 1, 2026
Completion
Jan 1, 2027

Study Design

Enrollment
52 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC

Arms

  • Active Comparator: Overactive Bladder Group
  • No Intervention: Healthy Group

Primary Outcome Measure

Changes in Urinary Biomarker Levels: * Quantitative measurement of urinary RhoA, NGF (Nerve Growth Factor), and BDNF (Brain-Derived Neurotrophic Factor) levels using the ELISA method. [ Time Frame: One year ]

Central Contacts

Related Studies