A Clinical Study of Ulonivirine (MK-8507) With Atorvastatin and Metformin in Healthy Adults (MK-8507-018)

Part of paid clinical trials in Tempe, Arizona.

Sponsor
Merck Sharp & Dohme LLC
Study ID
NCT07530289
Phase
PHASE1
Status
Completed

Conditions

  • Healthy

Eligibility Criteria

Sex
ALL
Age
18 Years - 55 Years
Healthy Volunteers
Accepted

Interventions

  • Atorvastatin — DRUG
    Oral tablet
  • Metformin — DRUG
    Oral tablet
  • Ulonivirine — DRUG
    Oral tablet

Study Details

Researchers want to learn about ulonivirine when given with atorvastatin and metformin in healthy people. The goal of this study is to compare the amount of atorvastatin and metformin in a person's body over time when given with and without ulonivirine.

Key Dates

First listed
Apr 15, 2026
Start date
Apr 29, 2026
Status verified
Jun 2026
Primary completion
May 23, 2026
Completion
Jun 3, 2026

Study Design

Enrollment
12 participants (actual)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Atorvastatin + metformin + ulonivirine
    In Period 1, participants will receive atorvastatin and metformin. In Period 2, participants will receive atorvastatin, metformin, and ulonivirine.

Primary Outcome Measure

Area Under the Concentration-Time Curve From Time 0 to Infinity (AUC0-inf) of Atorvastatin [ Time Frame: Day 1: Predose and at designated timepoints up to 72 hours post-dose ]

Locations (1)

FacilityCityStateZIPSite coordinators
Celerion ( Site 0001)TempeArizona85283-

Find similar trials in Tempe, AZ

By research site
Celerion· Tempe, AZ

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