A Study on Mucosal Specific IgA Immunokinetics After Administration of Nasal Spray Live Attenuated Influenza Vaccine
- Sponsor
- Changchun BCHT Biotechnology Co.
- Study ID
- NCT07545564
- Phase
- PHASE4
- Status
- Enrolling By Invitation
Conditions
- Influenza
Eligibility Criteria
- Sex
- ALL
- Age
- 3 Years - 17 Years
- Healthy Volunteers
- Accepted
Interventions
- LAIV — BIOLOGICALNasal spray live attenuated influenza vaccine
- Placebo — BIOLOGICALsterile water
Study Details
Mucosal-specific sIgA antibody GMT;Evaluate the achievement of 2-fold and 4-fold increases in the geometric mean titer (GMT) of specific nasal mucosal sIgA antibodies after vaccination
Key Dates
- First listed
- Apr 22, 2026
- Start date
- Apr 9, 2026
- Status verified
- Apr 2026
- Primary completion
- Apr 23, 2026
- Completion
- May 9, 2026
Study Design
- Enrollment
- 200 participants (estimated)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- PREVENTION
Arms
- Experimental: VaccineLAIV
- Placebo Comparator: Placebosterile water
Primary Outcome Measure
Membrane-specific sIgA antibody [ Time Frame: 14days after vaccination ]
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