Association Between Sarcopenia, Fatigue and Orthostatic Intolerance in Geriatric Patients: A Case Control Study

Sponsor
Ain Shams University
Study ID
NCT07564830
Status
Not Yet Recruiting

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Conditions

  • Fatigue
  • Orthostatic Intolerance
  • Sarcopenia

Eligibility Criteria

Sex
ALL
Age
65 Years - N/A
Healthy Volunteers
Accepted

Study Details

This study aims to explore the relationship between sarcopenia, fatigue, and orthostatic intolerance in older adults. It will be conducted among geriatric patients attending Ain Shams University Hospitals. Participants aged 65 years and older will be divided into two groups: those with sarcopenia, diagnosed according to the European Working Group on Sarcopenia in Older People 2, and age- and sex-matched controls without sarcopenia. The study will compare levels of fatigue and the presence of orthostatic intolerance between the two groups. The findings are expected to improve understanding of how sarcopenia is associated with fatigue and orthostatic symptoms in the elderly population, which may help guide better clinical assessment and management.

Key Dates

First listed
May 4, 2026
Start date
May 31, 2026
Status verified
Apr 2026
Primary completion
Jan 31, 2027
Completion
Apr 30, 2027

Study Design

Enrollment
90 participants (estimated)

Arms

  • Arm: cases
    Cases: Elderly patients (≥65 years) diagnosed with sarcopenia based on the European Working Group on Sarcopenia in Older People 2 (EWGSOP2) criteria.
  • Arm: controls
    Controls: Age- and sex-matched elderly patients without sarcopenia.

Primary Outcome Measure

Fatigue severity measured by Fatigue Severity Scale (FSS) [ Time Frame: Baseline ]

Central Contacts

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