Efficacy of Pulsed Electromagnetic Field Therapy on Women With Endometriosis

Sponsor
Beni-Suef University
Study ID
NCT07592403
Status
Recruiting
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Conditions

  • Endometriosis
  • Pulsed Electromagnetic Therapy
  • Trans Perineal Ultrasound

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 45 Years
Healthy Volunteers
Not accepted

Interventions

  • Pulsed Electromagnetic Field Therapy — DEVICE
    PEMF will be applied using a low-frequency pulsed electromagnetic stimulation device with sinusoidal waveform output targeting the lower abdominal and pelvic regions. Treatment sessions will be administered three times weekly for 8 consecutive weeks, with each session lasting approximately 20 minutes. Treatment parameters will include pulsed frequency ranging from 10 Hz, magnetic field intensity ranging from 2 mT, and pulse duration ranging from 250 microseconds. Standard medical care include stable hormonal therapy and prescribed analgesic medications without modification during the study period.
  • Sham pulsed electromagnetic field therapy — DEVICE
    Participants in this group will receive sham pulsed electromagnetic field therapy sessions in addition to stable standard medical care. The sham device will appear identical to the active device in shape, sound, and operating indicators without delivering therapeutic electromagnetic output. Session duration, participant positioning, and treatment frequency will match those of the experimental group.

Study Details

This randomized, sham-controlled, double-blinded clinical trial aims to investigate the effects of pulsed electromagnetic field therapy (PEMF) on pain intensity, quality of life, and pelvic floor morphometric changes assessed by four-dimensional trans perineal ultrasound (4D TPUS) in women diagnosed with endometriosis. Participants will be randomly allocated into either a PEMF therapy group or a sham PEMF control group. Both groups will continue receiving stable standard medical care throughout the study period. Assessments will be conducted at baseline, after completion of the 8-week intervention period, and at 3-month follow-up.

Key Dates

First listed
May 18, 2026
Start date
May 16, 2026
Status verified
May 2026
Primary completion
Jan 20, 2027
Completion
Jan 30, 2027

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Pulsed Electromagnetic Field Therapy Group
    Participants in this group will receive pulsed electromagnetic field therapy in addition to stable standard medical care.
  • Sham Comparator: Sham Pulsed Electromagnetic Field Therapy Group
    Participants in this group will receive sham pulsed electromagnetic field therapy sessions in addition to stable standard medical care.

Primary Outcome Measure

Endometriosis Health Profile-30 (EHP-30) questionnaire [ Time Frame: Baseline, 8 weeks and at 3-month follow-up. ]

Central Contacts

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