Early Cognitive Changes After Same-day Discharge Hip and Knee Arthroplasty

Sponsor
Odense University Hospital
Study ID
NCT07598552
Status
Recruiting
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Conditions

  • Cognitive Change
  • Postoperative Cognitive Dysfunction (POCD)
  • Total Knee Arthroplasty
  • Unicompartmental Knee Arthroplasty

Eligibility Criteria

Sex
ALL
Age
70 Years - N/A
Healthy Volunteers
Not accepted

Study Details

The goal of this observational study is to explore early cognitive changes in patients aged 70 years or older undergoing same-day discharge after hip or knee replacement surgery. The main question it aims to answer is: Does patients experience cognitive changes in cognitive test performance from before surgery to the first day after surgery? Participants will: * Complete a cognitive test battery virtually about 14 days before surgery, and on the first and seventh day after their operation. * Record pain levels and pain medicine use during the first week after surgery

Key Dates

First listed
May 20, 2026
Start date
May 18, 2026
Status verified
Jun 2026
Primary completion
Oct 31, 2026
Completion
Nov 30, 2026

Study Design

Enrollment
48 participants (estimated)

Arms

  • Arm: Total Hip Arthroplasty
    Patients aged 70 years or older undergoing elective unilateral total hip arthroplasty with planned discharge on the day of surgery.
  • Arm: Total Knee Arthroplasty
    Patients aged 70 years or older undergoing elective unilateral total knee arthroplasty with planned discharge on the day of surgery.
  • Arm: Unicompartmental Knee Arthroplasty
    Patients aged 70 years or older undergoing elective unilateral unicompartmental knee arthroplasty with planned discharge on the day of surgery.

Primary Outcome Measure

Change in Symbol Digit Modalities Test (SDMT) score from baseline to postoperative day 1. [ Time Frame: From baseline, 14 days before surgery, and postoperative day 1. ]

Central Contacts

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