High-Intensity Interval Training vs Moderate-Intensity Continuous Training in Phase II Cardiac Rehabilitation

Sponsor
Riphah International University
Study ID
NCT07619664
Status
Not Yet Recruiting

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Conditions

  • Coronary Artery Disease

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Not accepted

Interventions

  • High-Intensity Interval Training — BEHAVIORAL
    Participants will perform supervised treadmill-based high-intensity interval training 3 times per week. Each session includes 10 minutes warm-up, 4 intervals of 4 minutes at 85-95% heart rate reserve, 4 minutes active recovery at 50-60% heart rate reserve, followed by 5 minutes cool-down.
  • Moderate-Intensity Continuous Training — BEHAVIORAL
    Participants will perform supervised treadmill-based continuous exercise 3 times per week at 65-75% heart rate reserve for 30-45 minutes, including warm-up and cool-down periods.

Study Details

This randomized controlled trial aims to compare the effects of High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) in patients undergoing Phase II cardiac rehabilitation after coronary artery disease or post-angioplasty. A total of 66 participants will be randomly allocated into two groups: HIIT (n=33) and MICT (n=33). The intervention will be conducted 3 times per week using treadmill-based exercise protocols under heart rate monitoring. Primary outcomes include changes in left ventricular ejection fraction, functional capacity measured by 6-minute walk test, and lipid profile parameters before and after intervention. Secondary assessment includes health-related quality of life (HRQoL). The study aims to determine which exercise modality provides superior cardiovascular and functional improvement in stable cardiac patients during supervised rehabilitation.

Key Dates

First listed
Jun 2, 2026
Start date
Jun 30, 2026
Status verified
Jun 2026
Primary completion
Aug 31, 2026
Completion
Aug 31, 2026

Study Design

Enrollment
66 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: High-Intensity Interval Training (HIIT)
    Participants will perform supervised treadmill-based high-intensity interval training 3 sessions per week, including 10-minute warm-up, 4 intervals of 4 minutes at 85-95% heart rate reserve, 4-minute active recovery at 50-60% heart rate reserve, followed by 5-minute cool-down.
  • Active Comparator: Moderate-Intensity Continuous Training (MICT)
    Participants will perform supervised treadmill-based continuous exercise 3 sessions per week at 65-75% heart rate reserve for 30-45 minutes, with warm-up and cool-down periods.

Primary Outcome Measure

Left Ventricular Ejection Fraction [ Time Frame: Baseline and at 12 weeks after intervention ]

Central Contacts

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