The Role of Dietary Fiber in Mitigating Sarcopenia Risk in Head and Neck Cancer

Part of paid clinical trials in Oklahoma City, Oklahoma.

Sponsor
University of Oklahoma
Study ID
NCT07622914
Status
Recruiting
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Conditions

  • Head and Neck Cancers

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Study Details

Emerging data suggest consumption of dietary fiber before and during cancer treatment may improve prognosis for patients with head and neck cancer, in part via increased production of short chain fatty acids, systemic anti-inflammatory effects, and decreased risk of sarcopenia. Foods rich in dietary fiber are often low in calories and protein, thus are not typically targeted in current treatment paradigms that focus on countering the catabolic state associated with sarcopenia. This project entails an observational, mixed methods study to: observe dietary fiber intake in patients with head and neck cancer from time of diagnosis for six months; elucidate the relationship between dietary fiber intake, short chain fatty acids, inflammatory markers, and sarcopenia; and explore the feasibility of and patient perceptions regarding promoting dietary fiber as part of their treatment approaches.

Key Dates

Start date
Oct 31, 2025
Status verified
May 2026
Primary completion
Mar 31, 2027
Completion
Jun 30, 2027

Study Design

Enrollment
59 participants (estimated)

Arms

  • Arm: Head and neck cancer (HNC) patients
    Patients diagnosed with and undergoing treatment for head and neck cancer

Primary Outcome Measure

Dietary Fiber Intake (mean for 30 days) [ Time Frame: Baseline/upon enrollment, 3-months post-enrollment, and 6-months post-enrollment ]

Central Contacts

Locations (1)

FacilityCityStateZIP
Stephenson Cancer CenterOklahoma CityOklahoma73104

Find similar trials in Oklahoma City, OK

By research site
Stephenson Cancer Center· Oklahoma City, OK

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