Paid Clinical Trials in Oklahoma City, OK

As of August 2026, 592 paid clinical trials are recruiting in Oklahoma City, Oklahoma. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Oklahoma City offers studies at sites including University of Oklahoma Health Sciences Center for conditions such as Endometrial Cancer, Ovarian Cancer, Acute Myeloid Leukemia, Malignant Solid Neoplasm. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

Trials by specialty in Oklahoma City

Oncology· 266Women's health· 64Blood cancer· 49Gynecologic oncology· 47Cardiology· 40GI oncology· 37Behavioral health· 33Heart disease· 31Lung oncology· 27Lung disease· 26Autoimmune disease· 25Breast oncology· 23

Trials by drug in Oklahoma City

Methotrexate· 10Dexamethasone· 9Prednisone· 7Interview· 5Folinic acid· 5Letrozole· 4Prednisolone· 4SoC· 4Cystoscopy· 3Palbociclib· 3Mammography· 2Semaglutide· 2
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Newly added in Oklahoma City

Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.

540 clinical trials

Top Research Study Locations in Oklahoma City

Researchers run research studies in Oklahoma City, OK at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.

SiteSpecializes inActive trials
University of Oklahoma Health Sciences CenterAcute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Stage IVB Prostate Cancer AJCC v8183
Mercy Hospital Oklahoma CityMalignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v850
University of OklahomaEndometrial Cancer, Colorectal Cancer, Ovarian Cancer27
OU Health Stephenson Cancer CenterOvarian Cancer, AML With Mutated NPM1, Acute Myeloid Leukemia20
Stephenson Cancer CenterCervical Cancer, Endometrial Cancer, Ovarian Cancer14
Oklahoma Medical Research FoundationSystemic Lupus Erythematosus, Aging, Multiple Sclerosis11
The University of Oklahoma Health Sciences CenterARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome11
Hightower ClinicalAcute Migraine, Antineutrophil Cytoplasmic Antibody-associated Vasculitis, Cancer9
Oklahoma Heart HospitalAcute Decompensated Heart Failure, Aortic Stenosis, Atrial Fibrillation8
TSET Health Promotion Research CenterCRC (Colorectal Cancer), CRC Screening, Smoking Cessation8
Integris Southwest Medical CenterStage IIIB Lung Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma6
Lynn Health Science InstituteObesity or Overweight, Acne Vulgaris, Hypercholesterolemia6
Sooner Clinical ResearchMajor Depressive Disorder, Autism Spectrum Disorder, Bipolar Depression6
University of Oklahoma Health CampusAmyloid Pathology, Brain Activity, Brain Aging5
University of Oklahoma Health Science CenterAcute Lymphoblastic Leukemia (ALL), Acute Myelogenous Leukemia (AML or ANLL), Autoimmune Diseases5
Integris Baptist Medical CenterCardiovascular Diseases, Pulmonary Hypertension, Connective Tissue Diseases5
Integris Cancer Institute of OklahomaStage IIIB Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma, Advanced Gastric Adenocarcinoma4
Oklahoma Children's HospitalAnesthesia, Asthma Attack, Asthma in Children4
Oklahoma Proton CenterBreast Cancer, Breast Neoplasm, Breast Tumor4
Unity Clinical ResearchAtopic Dermatitis, Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa4
University of Oklahoma Health SciencesAcute Respiratory Distress Syndrome, Cancer Survivorship, Chemotherapy Side Effects4
Digestive Disease Specialists IncCrohn Disease, Colitis, Ulcerative3
GSK Investigational SiteAsthma, Alzheimer's Disease3
OU Health University of Oklahoma Medical CenterAcquired Antithrombin Deficiency, Carcinoma, Non-Small Cell Lung, Cutaneous Squamous Cell Cancer3
Oklahoma University Health Sciences CenterAdvanced Solid Tumors, Colorectal Cancer, Inflammation3

Active & Upcoming Studies in Oklahoma City (2026)

Recruiting trials in Oklahoma City grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.

Cancer & tumors (251 active studies)

Cardiovascular (39 active studies)

Diabetes & metabolic (26 active studies)

Neurology & pain (24 active studies)

Mental health & behavior (23 active studies)

Pediatric (7 active studies)

Vaccines (3 active studies)

Eye & vision (3 active studies)

Common conditions studied in Oklahoma City

Leading research sponsors in Oklahoma City

  • University of Oklahoma
  • National Cancer Institute (NCI)
  • Alliance for Clinical Trials in Oncology
  • SWOG Cancer Research Network
  • NRG Oncology

Frequently asked questions

How many paid clinical trials are currently recruiting in Oklahoma City?

There are approximately 592 recruiting clinical trials in Oklahoma City, Oklahoma listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Oklahoma City pay participants?

Most recruiting trials in Oklahoma City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Oklahoma City?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Oklahoma City?

The most common conditions under active study in Oklahoma City include Endometrial Cancer (16), Ovarian Cancer (14), Acute Myeloid Leukemia (13), Malignant Solid Neoplasm (10), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Oklahoma City?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Oklahoma City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Oklahoma City?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Oklahoma City?

Recruiting research sites in Oklahoma City include University of Oklahoma Health Sciences Center, Mercy Hospital Oklahoma City, University of Oklahoma, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Oklahoma City right now?

The largest active categories in Oklahoma City are Cancer & tumors (251), Cardiovascular (39), Diabetes & metabolic (26). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

Browse more clinical trials

Other cities in Oklahoma

Tulsa, OK(164)Edmond, OK(31)Lawton, OK(25)Norman, OK(25)Yukon, OK(11)Chickasha, OK(8)Bartlesville, OK(5)Ardmore, OK(3)Enid, OK(3)Moore, OK(3)Stillwater, OK(3)Ada, OK(2)Elk City, OK(2)Muskogee, OK(2)Tahlequah, OK(2)Altus, OK(1)Bethany, OK(1)Canton, OK(1)Duncan, OK(1)Durant, OK(1)Lindsay, OK(1)

Related healthcare resources in Oklahoma

Latest Oklahoma City, OK clinical trials research report

Trials by condition in Oklahoma City

Endometrial Cancer· 16Ovarian Cancer· 14Acute Myeloid Leukemia· 13Breast Cancer· 9Asthma· 8Major Depressive Disorder· 8