The Effect of Standard vs. Shorter Filter Lifespan During Continuous Renal Replacement Therapy

Sponsor
Universität Münster
Study ID
NCT07630220
Status
Not Yet Recruiting

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Conditions

  • Acute Kidney Injury

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • time span of filter change — OTHER
    The time span of the filter change during continuous renal replacement therapy will be specified

Study Details

This study aims to investigate shorter vs. standard filter lifespans in critically ill patients receiving continuous renal replacement therapy (CRRT) for acute kidney injury (AKI). The aim of this trial is to reliably implement,scheduled filter changes and to investigate whether shorter filter lifetime is associated with a lower incidence in rate of new infections.

Key Dates

First listed
Jun 5, 2026
Start date
Jun 30, 2026
Status verified
May 2026
Primary completion
Jun 30, 2028
Completion
Jun 30, 2028

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: Early filter change
    Scheduled filter change during continuous renal replacement therapy at 36 ± 3 hours.
  • Active Comparator: Standard of Care filter change
    Standard of care with scheduled filter change during continuous renal replacement therapy at 72 hours.

Primary Outcome Measure

Mean filter lifespan per patient [ Time Frame: From start of CRRT to end of CRRT or at day 30 after randomization, whatever occurs first ]

Central Contacts

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