Patient Navigation for Improving Transition Success Among Multiply Disadvantaged Young Adult Survivors of Childhood Cancer

Part of paid clinical trials in Los Angeles, California.

Sponsor
Children's Hospital Los Angeles
Study ID
NCT07630831
Status
Not Yet Recruiting

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Conditions

  • Cancer Childhood

Eligibility Criteria

Sex
ALL
Age
20 Years - 29 Years
Healthy Volunteers
Not accepted

Interventions

  • Navigation — BEHAVIORAL
    Follow Up
  • Control — BEHAVIORAL
    Standard of Care

Study Details

The goal of this clinical trial is to improve the successful healthcare transition from pediatric to adult-focused care for childhood cancer survivors. The main questions it aims to answer are * Receipt of the intervention (vs. standard of care control) will increase the proportion of CCS achieving transition success to adult-focused survivorship care from 50% to 70%. * Receipt of the intervention (vs. standard of care control) will significantly reduce patients' unmet HRSN. * Intervention effectiveness will be moderated by sociodemographic factors (gender, race/ethnicity, insurance status), medical risk for late effects, HRSN burden, and patient-reported outcomes (quality of life, self-efficacy). Researchers will compare those that receive intervention versus standard of care. Patients are randomized to either an intervention group, receiving structured PN-led sessions and tailored support for care transitions, or a control group receiving standard follow-up by a nurse case manager. High-HRSN patients in the intervention arm get monthly check-ins and coordinated handoffs to adult care providers for continuity.

Key Dates

Start date
Jul 1, 2026
Status verified
Jun 2026
Primary completion
Oct 1, 2029
Completion
Sep 1, 2030

Study Design

Enrollment
190 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Control
    Recontacting patients by a nurse case manager after transition launch to determine transition success.
  • Experimental: Navigation
    Patients in the intervention have phone or video session with patient navigator at enrollment, 6, 12 and 18 months, or more frequently as dictated by high-risk social needs.

Primary Outcome Measure

Proportion of participants with Transition to Adult-Focused Survivorship Care [ Time Frame: Within 18 months following transition "launch" (study enrollment/baseline) ]

Central Contacts

Locations (1)

FacilityCityStateZIP
Children's Hospital Los AngelesLos AngelesCalifornia90027

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