Assessment of Renal Perfusion Using Ultrasound and Near-Infrared Spectroscopy in Patients Undergoing Minimally Invasive Abdominal Surgery

Sponsor
Istanbul University - Cerrahpasa
Study ID
NCT07635160
Status
Recruiting
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Conditions

  • Acute Kidney Injury
  • Minimally Invasive Surgical Procedures
  • Renal Perfusion

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Study Details

This prospective observational study aims to evaluate renal perfusion in adult patients undergoing elective minimally invasive abdominal surgery. Renal perfusion will be assessed using two non-invasive monitoring techniques: Doppler ultrasonography-derived Renal Resistive Index (RRI) and Near-Infrared Spectroscopy (NIRS)-derived renal regional oxygen saturation (rSO₂). Measurements will be obtained at predefined perioperative time points, including after induction of anesthesia, during pneumoperitoneum, before extubation, and during the early postoperative period. Perioperative changes in renal perfusion parameters will be analyzed and correlated with clinical variables such as intra-abdominal pressure, pneumoperitoneum duration, hemodynamic parameters, fluid administration, urine output, and postoperative renal function. The study also aims to investigate the relationship between intraoperative renal perfusion changes and the development of postoperative acute kidney injury. The findings may contribute to improved perioperative monitoring and optimization of renal perfusion during minimally invasive abdominal surgery.

Key Dates

First listed
Jun 9, 2026
Start date
Jan 7, 2026
Status verified
Jun 2026
Primary completion
Jan 7, 2027
Completion
Jan 7, 2027

Study Design

Enrollment
51 participants (estimated)

Arms

  • Arm: Elective Minimally Invasive Abdominal Surgery Patients
    Adult patients aged 18 to 80 years undergoing elective minimally invasive abdominal surgery under general anesthesia. Renal perfusion will be assessed perioperatively and postoperatively(postoperative 1. hour) using Doppler ultrasonography-derived Renal Resistive Index (RRI) and Near-Infrared Spectroscopy (NIRS)-derived regional renal oxygen saturation (rSO₂). Measurements will be performed at predefined perioperative time points and correlated with intraoperative variables, postoperative renal function, and the occurrence of acute kidney injury.

Primary Outcome Measure

Change in Renal Regional Oxygen Saturation Measured by NIRS [ Time Frame: after endotracheal intubation, immediately before extubation, and 1 hour after extubation ]

Central Contacts

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