Pulmonary Hypertension (PH) Biorepository for Translational Research

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
National Institutes of Health Clinical Center (CC)
Study ID
NCT07647549
Status
Not Yet Recruiting

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Conditions

  • Pulmonary Hypertension

Eligibility Criteria

Sex
ALL
Age
18 Years - 100 Years
Healthy Volunteers
Not accepted

Study Details

Background: Pulmonary hypertension (PH) is high blood pressure in the blood vessels of the lungs. It can lead to heart failure and death if not treated. Researchers want to create a repository of blood samples and health information collected from people with PH. They hope to use this information to find better ways to diagnose and treat PH. Objective: To collect blood samples and health information from people suspected of or diagnosed with PH. Eligibility: People aged 18 years and older who have or may have PH. Design: Researchers will collect information from participants medical records. Participants will have blood drawn from a vein. About 3 tablespoons will be collected during the study visit. The visit will last about 1 hour. Participants may choose to provide new blood samples at follow-up visits. Updated medical information may also be collected. Participants may continue to participate as long as the study is ongoing. Participants may opt out of providing new blood samples but remain in the study. All study samples will be stored at the National Institutes of Health. Health information will be stored in secure databases.

Key Dates

First listed
Jun 15, 2026
Start date
Aug 3, 2026
Status verified
Jun 2026
Primary completion
Jun 1, 2036
Completion
Jun 1, 2036

Study Design

Enrollment
1,000 participants (estimated)

Arms

  • Arm: Group 1 (suspected of or diagnosed)
    Pulmonary Arterial Hypertension, PAH
  • Arm: Group 2 (suspected of or diagnosed)
    PH due to left heart disease
  • Arm: Group 3 (suspected of or diagnosed)
    PH due to lung diseases and/or hypoxia
  • Arm: Group 4 (suspected of or diagnosed)
    PH due to thromboembolic disease
  • Arm: Group 5 (suspected of or diagnosed)
    PH with unclear or multifactorial mechanisms

Primary Outcome Measure

Develop a multi-center biorepository. [ Time Frame: 10 years ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
University of Maryland Medical Center at Baltimore (UMB)BaltimoreMaryland21201
Gautam Ramani
[email protected]
Not Listed
Bradley Maron
[email protected]
Not Listed
National Institutes of Health Clinical CenterBethesdaMaryland20892
NIH Clinical Center Office of Patient Recruitment (OPR)
[email protected]
800-411-1222
INOVA Fairfax HospitalFalls ChurchVirginia22042-

Find similar trials in Baltimore, MD

By research site
University of Maryland Medical Center at Baltimore (UMB)· Baltimore, MDNational Institutes of Health Clinical Center· Bethesda, MDINOVA Fairfax Hospital· Falls Church, VA

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