Risk Factor Assessment for Acute Pulmonary Hypertension Crisis

Sponsor
Peking Union Medical College Hospital
Study ID
NCT07653958
Status
Recruiting
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Conditions

  • Pulmonary Hypertension
  • Pulmonary Hypertension Crisis

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Study Details

The goal of this observational study is to learn about pulmonary hypertension crisis (PHC) - a severe, and often fatal complication - in patients with pulmonary hypertension (PH). The main questions this study aims to answer are: What are the clinical and hemodynamic features of PHC, and what underlying pathophysiological mechanisms cause it to develop? Can these features be used to diagnostic PHC, predict who is at risk of developing it or dying from it, and develop targeted prevention and treatment of PHC? A multi-center registry platform and biobank will be established to enroll and follow up patients with PH. Clinical data, hemodynamic measurements, and biological specimen will be collected. Risk prediction and early warning tools of PHC will be developed.

Key Dates

First listed
Jun 17, 2026
Start date
Jun 17, 2026
Status verified
Jun 2026
Primary completion
Jun 30, 2029
Completion
Dec 31, 2029

Study Design

Enrollment
5,000 participants (estimated)

Arms

  • Arm: Pulmonary hypertension
    Patients with right heart catheter confirmed pulmonary hypertension

Primary Outcome Measure

Pulmonary hypertension crisis [ Time Frame: From enrollment to 3 years after enrollment ]

Central Contacts

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