Goji Berry and Vasomotor Symptoms Pilot Study

Part of paid clinical trials in Davis, California.

Sponsor
University of California, Davis
Study ID
NCT07660315
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
FEMALE
Age
40 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Goji Berry Juice Powder — OTHER
    Participants will be instructed to consume 2 tbsp of goji berry juice powder in the form of a mug cake daily for one month
  • Goji Berry Powder — OTHER
    Participants will be instructed to consume 2 tbsp of goji berry powder in the form of a mug cake daily for a month

Study Details

The goal of this clinical trial is to compare two forms of goji berry powder-whole goji berry powder and goji juice powder-in peri- and postmenopausal women aged 40-65 years who experience frequent vasomotor symptoms (hot flashes). The study aims to determine which formulation is more promising for a future larger trial by evaluating effects on HDL cholesterol function, vasomotor symptoms, cognitive performance, and participant acceptability. The main questions it aims to answer are: Does whole goji berry powder produce a greater improvement in HDL cholesterol efflux capacity (CEC) over 30 days compared with goji juice powder? Are changes in HDL function associated with changes in hot flash burden, cognitive performance, and self-reported cognitive symptoms? Researchers will compare participants assigned to whole goji berry powder with participants assigned to goji juice powder to evaluate differences in HDL function, vasomotor symptoms, cognitive outcomes, and intervention acceptability. Participants will: Consume one mug cake containing their assigned goji powder daily for 30 days. Record hot flash frequency, duration, and severity using a smartphone-based electronic diary. Attend study visits at baseline, Day 15, and Day 30. Provide fasting blood samples at baseline and Day 30 for assessment of HDL cholesterol efflux capacity and cardiometabolic biomarkers. Complete computerized cognitive testing (TabCAT) at baseline and Day 30. Complete questionnaires assessing menopause-related quality of life, brain fog, mental alertness, physical activity, and study acceptability.

Key Dates

Start date
Jun 25, 2026
Status verified
Jun 2026
Primary completion
Jun 30, 2027
Completion
Oct 31, 2027

Study Design

Enrollment
6 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Active Comparator: Goji Berry Juice Powder
    In this arm, participants consume goji berry juice powder
  • Experimental: Goji Berry Powder
    In this arm, participants will consume goji berry powder

Primary Outcome Measure

High-Density Lipoprotein (HDL) Cholesterol Efflux Capacity (CEC) [ Time Frame: 1 month ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Ragle Human Nutrition Research CenterDavisCalifornia95616
Qianyue (Betty) Sun, MS, RD
[email protected]
512-905-2364
Angela M Zivkovic, PhD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Davis, CA

By condition
Menopause
By specialty
Women's healthFertility
By research site
Ragle Human Nutrition Research Center· Davis, CA

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