A Study of CRD3874-SI in People With Leukemia

Part of paid clinical trials in Basking Ridge, New Jersey.

Sponsor
Memorial Sloan Kettering Cancer Center
Study ID
NCT07661095
Phase
PHASE1
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • CRD3874-SI — DRUG
    CRD3874-SI is a STING (Stimulator of Interferon Genes) agonist in participants with relapsed and refractory (R/R) acute myeloid leukemia (AML).

Study Details

The purpose of this study is to find out whether CRD3874-SI is a safe treatment for participants with acute myeloid leukemia (AML).

Key Dates

Start date
Jun 15, 2026
Status verified
Jun 2026
Primary completion
Jun 15, 2028
Completion
Jun 15, 2028

Study Design

Enrollment
24 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: 0.6 mg/kg CRD3874-SI
  • Experimental: 0.9 mg/kg CRD3874-SI
  • Experimental: 1.4 mg/kg CRD3874-SI

Primary Outcome Measure

Maximum tolerated dose of CRD3874-SI [ Time Frame: up to 1 year ]

Central Contacts

Locations (7)

FacilityCityStateZIPSite coordinators
Memorial Sloan Kettering at Basking Ridge (All Protocol Activities)Basking RidgeNew Jersey07920
Eytan Stein, MD
646-608-3749
Memorial Sloan Kettering Monmouth (All protocol activities)MiddletownNew Jersey07748
Eytan Stein, MD
646-608-3749
Memorial Sloan Kettering Bergen (All Protocol Activities)MontvaleNew Jersey07645
Eytan Stein, MD
646-608-3749
Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities)CommackNew York11725
Eytan Stein, MD
646-608-3749
Memorial Sloan Kettering Westchester (All protocol activities)HarrisonNew York10604
Eytan Stein, MD
646-608-3749
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New YorkNew York10065
Eytan Stein, MD
646-608-3749
Aaron Goldberg, MD, Phd
646-608-3752
Memorial Sloan Kettering Nassau (All Protocol Activities)Rockville CentreNew York11553
Eytan Stein, MD
646-608-3749

Find similar trials in Basking Ridge, NJ

By condition
Leukemia (other)
By specialty
OncologyBlood cancer
By research site
Memorial Sloan Kettering at Basking Ridge (All Protocol Activities)· Basking Ridge, NJMemorial Sloan Kettering Monmouth (All protocol activities)· Middletown, NJMemorial Sloan Kettering Bergen (All Protocol Activities)· Montvale, NJMemorial Sloan Kettering Suffolk-Commack (All Protocol Activities)· Commack, NYMemorial Sloan Kettering Westchester (All protocol activities)· Harrison, NYMemorial Sloan Kettering Cancer Center (All Protocol Activities)· New York, NY

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