Resting Energy Expenditure in Pediatric Patients With Inflammatory Bowel Disease (REE-MICI)

Sponsor
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Study ID
NCT07670975
Status
Recruiting
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Conditions

  • Colitis, Ulcerative
  • Crohn Disease Colitis
  • Inflammatory Bowel Diseases

Eligibility Criteria

Sex
ALL
Age
6 Years - 17 Years
Healthy Volunteers
Not accepted

Interventions

  • Indirect Calorimetry — DIAGNOSTIC_TEST
    Resting energy expenditure (REE) assessment performed using indirect calorimetry in pediatric patients with inflammatory bowel disease during routine clinical follow-up. Measurements are obtained under resting conditions after fasting and are used to evaluate energy metabolism and its relationship with disease activity and treatments.

Study Details

This multicenter prospective observational non-pharmacological study aims to evaluate resting energy expenditure (REE) in pediatric patients affected by inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. REE will be measured using indirect calorimetry and estimated using predictive equations. The study also aims to investigate the relationship between REE, disease activity, and dietary or pharmacological treatments. Clinical, laboratory, anthropometric, nutritional, and disease activity data will be collected during routine clinical follow-up at diagnosis, after induction therapy, and during follow-up visits.

Key Dates

First listed
Jun 26, 2026
Start date
May 1, 2025
Status verified
Jun 2026
Primary completion
Mar 31, 2027
Completion
Nov 30, 2027

Study Design

Enrollment
50 participants (estimated)

Arms

  • Arm: Pediatric IBD Patients
    Pediatric patients aged 6 to 17 years with a new diagnosis of inflammatory bowel disease, including Crohn disease and ulcerative colitis, enrolled in this prospective multicenter observational study. Participants undergo resting energy expenditure assessment by indirect calorimetry together with routine clinical, laboratory, anthropometric, nutritional, and disease activity evaluations during follow-up.

Primary Outcome Measure

Resting Energy Expenditure measured by indirect calorimetry [ Time Frame: Baseline, 2 months, and 9 months after diagnosis ]

Central Contacts

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