A Clinical Trial of MK-1403 in Healthy Participants (MK-1403-007)

Part of paid clinical trials in Miami, Florida.

Sponsor
Merck Sharp & Dohme LLC
Study ID
NCT07677163
Phase
PHASE1
Status
Recruiting
Apply to this trial

Conditions

  • Healthy

Eligibility Criteria

Sex
ALL
Age
18 Years - 55 Years
Healthy Volunteers
Accepted

Interventions

  • MK-1403 formulation (FM) 1 + additive — DRUG
    Oral tablet
  • MK-1403 FM2 + additive — DRUG
    Oral tablet

Study Details

The purpose of this trial is to learn about a trial medicine called MK-1403. Researchers designed MK-1403 to treat a type of heart and blood vessel disease called atherosclerotic cardiovascular disease (ASCVD). Before giving a trial medicine to people with a health condition, researchers first do clinical trials in healthy people. This trial will help researchers learn about the safety of MK-1403 and if participants tolerate it. Tolerate means participants receive the trial medicine and they do not need to stop taking it due to health problems. The trial will also measure what happens to MK 1403 in a healthy person's body over time.

Key Dates

First listed
Jun 30, 2026
Start date
Aug 14, 2026
Status verified
Aug 2026
Primary completion
Sep 22, 2026
Completion
Sep 22, 2026

Study Design

Enrollment
15 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: MK-1403 formulation (FM) 1 + additive, Fed
    MK-1403 FM 1 + additive tablet administered once orally at study dose after a high-fat meal.
  • Experimental: MK-1403 FM1 + additive, Fasted
    MK-1403 FM1 + additive tablet administered once orally at study dose in a fasted state.
  • Experimental: MK-1403 FM2 + additive, Fed
    MK-1403 FM2 tablet + additive administered once orally at study dose after a high-fat meal.

Primary Outcome Measure

Number of Participants Who Experience an Adverse Event (AE) [ Time Frame: Up to approximately 4 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Qps-Mra, LlcMiamiFlorida33143
Study Coordinator

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Qps-Mra, Llc· Miami, FL

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