Prevalence of Chapman Reflex Points in Medical Students and Their Association With Visceral Symptoms

Part of paid clinical trials in New York, New York.

Sponsor
The Touro College and University System
Study ID
NCT07691112
Status
Completed

Conditions

  • Autonomic Nervous System Diseases
  • Chapman Reflex Points
  • Healthy
  • Lymphatic Diseases
  • Somatic Dysfunction

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Chapman Reflex Point Examination — PROCEDURE
    Participants underwent a standardized palpatory examination of established Chapman Reflex Point locations performed by a single trained investigator who was blinded to questionnaire responses. Consistent pressure application and examination duration were utilized to optimize reliability and reproducibility of palpatory findings. No therapeutic intervention, osteopathic manipulative treatment, medication administration, or other clinical intervention was provided as part of the study. Participants also completed a standardized health questionnaire assessing demographic characteristics, medical history, lifestyle factors, and recent or recurrent visceral symptoms.

Study Details

Chapman Reflex Points (CRPs) are small palpable nodules found within connective tissue that have traditionally been associated with dysfunction of internal organs and the autonomic nervous system. However, little is known about how commonly these findings occur in healthy individuals or whether they are associated with symptoms experienced by otherwise healthy people. The purpose of this study is to determine the prevalence of Chapman Reflex Points in young healthy adults and to evaluate whether the presence and distribution of these points are associated with self-reported visceral symptoms. Participants complete a standardized health questionnaire regarding recent and recurrent symptoms and undergo a blinded physical examination of established Chapman Reflex Point locations performed by a trained investigator. The results of this study may improve understanding of the physiological mechanisms underlying Chapman Reflex Points and help clarify their potential role in preventive osteopathic assessment and early identification of altered autonomic, lymphatic, fascial, or neuroendocrine function.

Key Dates

First listed
Jul 8, 2026
Start date
Mar 4, 2020
Status verified
Jun 2026
Primary completion
Jun 26, 2026
Completion
Jun 27, 2026

Study Design

Enrollment
101 participants (actual)

Arms

  • Arm: Healthy Young Adults
    Participants were young adults who completed a standardized health questionnaire assessing demographic characteristics, medical history, lifestyle factors, and recent or recurrent visceral symptoms. Participants subsequently underwent a blinded palpatory examination of established Chapman Reflex Point locations performed by a trained investigator. No therapeutic intervention was administered. The study evaluated the prevalence and distribution of Chapman Reflex Points and their associations with self-reported visceral symptom clusters.

Primary Outcome Measure

Prevalence of Chapman Reflex Points [ Time Frame: through study completion, an average of 1 year ]

Locations (1)

FacilityCityStateZIPSite coordinators
Touro College of Osteopathic Medicine - HarlemNew YorkNew York10027-

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By research site
Touro College of Osteopathic Medicine - Harlem· New York, NY

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