Moving Yourself in Space and Time: MYSTIC

Part of paid clinical trials in Atlanta, Georgia.

Sponsor
Emory University
Study ID
NCT07697664
Status
Recruiting
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Conditions

  • Alzheimer's Disease (AD) and Related Disorders
  • Older Adults (60 - 85 Years Old)
  • Parkinson's Disease (PD)

Eligibility Criteria

Sex
ALL
Age
18 Years - 79 Years
Healthy Volunteers
Accepted

Interventions

  • Complex Rhythmic Movement Sequences (CRMS) Sessions — OTHER
    Researchers will establish complex rhythmic movement sequences (CRMS) as an experimental paradigm to identify spatial and temporal components and learning time courses of complex rhythmic movement. Participants will dance with new partners every 15-20 minutes, a widely practiced method of the dance community to enhance learning. The class format is: 1. practicing previously learned steps 2. 25-minute warmup, partnering/rhythmic exercises 3. learning new steps 4. combining old and new steps 5. cool down Participants dance both leading and following roles, learn how to interpret motor goals through touch, and perform activities to foster understanding of the temporal relationship of movement to music.

Study Details

This study is being done to answer the question: Do people with Parkinson's benefit from a new stepping therapy, and how do people with Parkinson's best learn new steps and rhythms set to music? Researchers will also compare individuals with Parkinson's Disease with people with Mild Cognitive Impairment, and with people with neither of these conditions. The purpose of this study is to identify principles of human-music interactions to establish underlying guiding theories for application to music-based rehabilitation for older populations with neurodegenerative disease, leading to more refined and targeted music-based rhythmic movement therapies.

Key Dates

First listed
Jul 13, 2026
Start date
Mar 25, 2022
Status verified
Jul 2026
Primary completion
Dec 31, 2028
Completion
Dec 31, 2028

Study Design

Enrollment
210 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Older adults with MCI
    Participants will attend daily (3-5 times/week) lessons that will last 1.5h for a month (e.g., 3-5 weeks) and will receive contact and monitoring from study staff. The Principal Investigator will monitor fidelity via weekly reports from interventionists.
  • Active Comparator: Older adults without MCI
    Participants will attend daily (3-5 times/week) lessons that will last 1.5h for a month (e.g., 3-5 weeks) and will receive contact and monitoring from study staff. The Principal Investigator will monitor fidelity via weekly reports from interventionists.
  • Experimental: Older adults with PD
    Participants will attend daily (3-5 times/week) lessons that will last 1.5 h for a month (e.g., 3-5 weeks) and will receive contact and monitoring from study staff. The Principal Investigator will monitor fidelity via weekly reports from interventionists.
  • Active Comparator: Young adults and adults with normal cognition (NC)
    Participants will attend daily (3-5 times/week) lessons that will last 1.5h for a month (e.g., 3-5 weeks) and will receive contact and monitoring from study staff. The Principal Investigator will monitor fidelity via weekly reports from interventionists.

Primary Outcome Measure

Four-Square Step Test (FSST) [ Time Frame: Baseline and post-intervention (3 to 5 weeks) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Emory University, Executive Park, Wesley WoodsAtlantaGeorgia30329
Madeleine E. Hackney, PhD
[email protected]

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By research site
Emory University, Executive Park, Wesley Woods· Atlanta, GA

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