Identification of Genes of Interest for Severe Forms of Preeclampsia

Sponsor
University Hospital, Strasbourg, France
Study ID
NCT07703826
Status
Not Yet Recruiting

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Conditions

  • Preeclampsia
  • Severe Preeclampsia

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 45 Years
Healthy Volunteers
Not accepted

Study Details

Preeclampsia is a pregnancy complication characterized by high blood pressure associated with damage to various organs, especially the kidneys. It happens in about 1 to 5% of pregnant women and can cause serious problems for both the mother and the baby. Several multi-omics studies have already been conducted on preeclampsia, with promising results. However, this is preliminary data that requires further studies. The molecular markers identified in this type of study could potentially be used, first of all, for the early screening of this condition, which is not yet reliably achievable. In addition, the knowledge gained from this research would help us better understand the pathophysiology of preeclampsia. Therefore, the investigators' goal is to carry out a multi-omics analysis of preeclampsia to uncover the genetic and molecular mechanisms involved in this condition.

Key Dates

First listed
Jul 14, 2026
Start date
Sep 1, 2026
Status verified
Jul 2026
Primary completion
Sep 1, 2029
Completion
Jan 1, 2031

Study Design

Enrollment
100 participants (estimated)

Arms

  • Arm: Experimental group P
    a group of 50 pregnant women with severe preeclampsia
  • Arm: Control group T
    a control group of 50 pregnant women without any medical conditions.

Primary Outcome Measure

Identifying genetic and molecular markers associated with severe forms of preeclampsia [ Time Frame: At enrollment ]

Central Contacts

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