BIOANCIENT: Cohort of Centenarians in Navarra (1926-1927)

Sponsor
Fundacion Miguel Servet
Study ID
NCT07707297
Status
Recruiting
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Conditions

  • Age-Related Diseases
  • Aging
  • Biomarkers / Blood
  • Cellular Senescence
  • Frailty

Eligibility Criteria

Sex
ALL
Age
100 Years - N/A
Healthy Volunteers
Not accepted

Study Details

Demographic aging is a growing global challenge, driven by increasing life expectancy and declining birth rates, with projections indicating that more than 30% of the European population will be over 65 years old by 2100. Centenarians represent a unique biological model of extreme longevity, often exhibiting delayed onset of age-related diseases and preserved functional capacity. This study aims to establish an intergenerational cohort of centenarians in Navarra (Spain) to investigate the biological, clinical, environmental, and lifestyle factors associated with extreme longevity. By integrating multidimensional data-including clinical assessments, functional and cognitive measures, and biological markers-this study seeks to improve understanding of aging mechanisms and identify potential determinants of healthy aging.

Key Dates

First listed
Jul 16, 2026
Start date
Feb 4, 2026
Status verified
Jul 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
333 participants (estimated)

Arms

  • Arm: Centenarians resident in Navarre - Spain
    Centenarians (individuals aged ≥100 years) residing in Navarre, Spain.

Primary Outcome Measure

Integrated biological aging profile based on clinical and multi-omics biomarkers. [ Time Frame: Baseline and 1-year follow-up ]

Central Contacts

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