The Effect of Early Intervention on the Incidence of Posttraumatic Stress Disorder After Intensive Care Hospitalization Due to Sepsis

Sponsor
Barzilai Medical Center
Study ID
NCT07707765
Status
Recruiting
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Conditions

  • ICU
  • PTSD - Post Traumatic Stress Disorder
  • Sepsis

Eligibility Criteria

Sex
ALL
Age
18 Years - 120 Years
Healthy Volunteers
Not accepted

Interventions

  • Psychiatric interview — OTHER
    Psychiatric interview for 45 minutes

Study Details

In recent years, the survival rate among intensive care patients has improved due to advancements in diagnosing severe infections and the use of broad-spectrum antibiotics. However, many survivors face long-term complications, known as Post-Intensive Care Syndrome (PICS), including physical, cognitive, and psychological impairments such as post-traumatic stress disorder (PTSD), anxiety, and depression. Approximately 9-27% of ICU survivors develop these symptoms, particularly those hospitalized due to sepsis. Common risk factors include traumatic hospital experiences, delirium, and extended mechanical ventilation. Despite the prevalence of these issues, most medical centers lack structured models for screening and early intervention, highlighting the need for evaluations of early intervention strategies to support at-risk patients post-discharge and improve their quality of life.

Key Dates

First listed
Jul 16, 2026
Start date
Jul 1, 2026
Status verified
Jul 2026
Primary completion
Oct 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: Early psychiatric intervention
    Interventional arm. Early intervention after discharge from ICU.
  • No Intervention: No intervention
    Observational arm. No intervention after discharge from ICU.

Primary Outcome Measure

PTSD risk according to PCL-5 [ Time Frame: 30 days ]

Central Contacts

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