Salivary Cytokines, MMP-8 and Dental Caries in Osteoporosis Patients

Sponsor
Afyonkarahisar Health Sciences University
Study ID
NCT07709247
Status
Not Yet Recruiting

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Conditions

  • Biomarkers
  • Dental Caries
  • Matrix Metalloproteinase 8
  • Osteoporosis

Eligibility Criteria

Sex
ALL
Age
45 Years - 75 Years
Healthy Volunteers
Accepted

Study Details

This study examines saliva samples from patients with osteoporosis. The levels of cytokines and Matrix Metalloproteinase-8 (MMP-8) enzyme in saliva will be measured. Additionally, the dental caries status of participants will be evaluated. The aim of this study is to understand the relationship between osteoporosis and oral health. Only saliva samples will be collected from participants; no treatment or medication will be administered.

Key Dates

First listed
Jul 16, 2026
Start date
Jul 10, 2026
Status verified
Jul 2026
Primary completion
Sep 30, 2026
Completion
Jul 10, 2027

Study Design

Enrollment
50 participants (estimated)

Arms

  • Arm: Osteoporosis Group
    Patients diagnosed with osteoporosis. Saliva samples will be collected to measure cytokine levels and MMP-8.
  • Arm: Control Group
    Healthy individuals without osteoporosis. Saliva samples will be collected for comparison.

Primary Outcome Measure

Salivary Cytokine Levels [ Time Frame: day 1 ]

Central Contacts

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