Analgesia Methods and Early Mobilization in Geriatric ICU Patients After Major Surgery

Sponsor
Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Study ID
NCT07709975
Status
Recruiting
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Conditions

  • Delirium - Postoperative
  • Frailty
  • Postoperative Care in Geriatric Intensive Care Patients
  • Postoperative Pain

Eligibility Criteria

Sex
ALL
Age
65 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Systemic Opioid Analgesia (± Multimodal) — DRUG
    Standard-of-care intravenous opioid-based analgesia, with or without additional non-opioid multimodal agents, administered per routine clinical practice.
  • Epidural Analgesia — PROCEDURE
    Standard-of-care epidural analgesia administered per routine clinical practice.
  • Peripheral Nerve Block (± Multimodal) — PROCEDURE
    Standard-of-care peripheral nerve block analgesia, with or without additional non-opioid multimodal agents, administered per routine clinical practice.

Study Details

This study looks at how different pain-control methods affect how quickly older adults get out of bed and start moving again after major surgery. Researchers will observe patients aged 65 and older who are admitted to the intensive care unit (ICU) after major surgery. Doctors will use their usual pain-control methods - either medication given through a vein, an epidural, or a nerve block - based on standard clinical practice; the study team will not change or choose the treatment. The study will record how long it takes for each patient to first sit up, stand, or walk after surgery, along with pain levels, confusion (delirium), how satisfied patients are with their pain control, and how long they stay in the ICU. The goal is to better understand which pain-control approaches may help older patients recover and move more quickly and safely after major surgery.

Key Dates

First listed
Jul 17, 2026
Start date
Jun 15, 2026
Status verified
Jul 2026
Primary completion
Sep 15, 2026
Completion
Sep 15, 2026

Study Design

Enrollment
90 participants (estimated)

Arms

  • Arm: Systemic Analgesia
    Patients who receive systemic (intravenous) opioid analgesia, with or without multimodal analgesic agents, as determined by the treating clinical team.
  • Arm: Epidural Analgesia
    Patients who receive epidural analgesia as determined by the treating clinical team.
  • Arm: Peripheral Nerve Block
    Patients who receive peripheral nerve block analgesia, with or without multimodal analgesic agents, as determined by the treating clinical team.

Primary Outcome Measure

Time to First Mobilization [ Time Frame: From ICU admission until first achievement of ICU Mobility Scale level ≥1, assessed for up to 30 days. ]

Central Contacts

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