Histological Assessment of Tissue Penetration Depth of Argon Beam Coagulation in Ovarian Endometriomas

Sponsor
Insel Gruppe AG, University Hospital Bern
Study ID
NCT07711743
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 40 Years
Healthy Volunteers
Not accepted

Interventions

  • Argon Plasma Coagulation — PROCEDURE
    Standardized argon plasma coagulation (APC) is applied to the outer surface of the ovarian endometrioma capsule immediately before laparoscopic cystectomy. The resected tissue is subsequently processed for histological analysis to assess the depth of APC tissue penetration.

Study Details

The goal of this clinical trial is to evaluate the depth of tissue penetration of Argon Beam Coagulation (ABC) during laparoscopic surgery for ovarian endometriomas. Researchers want to determine how deeply ABC affects ovarian tissue and to generate data on the safety of this surgical technique. Participants will undergo standard laparoscopic surgery for ovarian endometriomas. During the planned surgical procedure, Argon Beam Coagulation will be applied to the ovarian surface according to the study protocol. The treated tissue will subsequently be excised as part of the planned surgery and analyzed histologically to measure the depth of tissue penetration.

Key Dates

First listed
Jul 17, 2026
Start date
Jul 9, 2026
Status verified
Jul 2026
Primary completion
Jul 7, 2027
Completion
Aug 7, 2027

Study Design

Enrollment
50 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Argon Plasma Coagulation Before Ovarian Endometrioma Cystectomy
    Participants undergo standardized argon plasma coagulation (APC) on the surface of the ovarian endometrioma capsule immediately before laparoscopic cystectomy. The resected capsule is subsequently analyzed histologically to determine the depth of APC tissue penetration

Primary Outcome Measure

Depth of thermal tissue effects in the ovarian endometrioma cyst wall [ Time Frame: Immediately after surgery (Day 0) ]

Central Contacts

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