Corneal Biomechanics and Surgically Induced Astigmatism in Pseudoexfoliation Syndrome

Sponsor
Kata Culina
Study ID
NCT07722247
Status
Recruiting
Apply to this trial

Conditions

  • Astigmatism
  • Cataract
  • Pseudoexfoliation Syndrome

Eligibility Criteria

Sex
ALL
Age
50 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • phacoemulsification cataract surgery — PROCEDURE
    Standard phacoemulsification cataract surgery with intraocular lens implantation performed according to routine clinical practice.

Study Details

This prospective study aims to evaluate the influence of corneal biomechanical properties on surgically induced astigmatism following standard phacoemulsification cataract surgery in patients with pseudoexfoliation syndrome compared with patients without pseudoexfoliation. Corneal hysteresis (CH), corneal resistance factor (CRF) and corneal astigmatism will be measured before surgery and at postoperative follow-up visits. The relationship between changes in corneal biomechanics and surgically induced astigmatism will be analyzed.

Key Dates

First listed
Jul 23, 2026
Start date
Jul 20, 2026
Status verified
Aug 2026
Primary completion
Oct 31, 2026
Completion
Oct 31, 2026

Study Design

Enrollment
70 participants (estimated)

Arms

  • Arm: Pseudoexfoliation syndrome
    Patients with pseudoexfoliation syndrome undergoing standard phacoemulsification cataract surgery
  • Arm: Control group
    Patients without pseudoexfoliation syndrome undergoing standard phacoemulsification cataract surgery

Primary Outcome Measure

Correlation between corneal biomechanical properties and surgically induced astigmatism [ Time Frame: Preoperative, postoperative day 1, postoperative day 7, and postoperative day 30. ]

Central Contacts

Related Studies