BIOANCIENT_EX: Effects of a Physical Exercise Program in Centenarians of the BIOANCIENT Cohort: A Randomized Clinical Trial.

Sponsor
Fundacion Miguel Servet
Study ID
NCT07723339
Status
Enrolling By Invitation

Conditions

  • Aging
  • Biomarkers / Blood
  • Cellular Senescence
  • Exercise
  • Frailty

Eligibility Criteria

Sex
ALL
Age
100 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Exercise — OTHER
    Participants in the intervention group will take part in an individualized multicomponent physical training program including exercises targeting strength, balance, and aerobic capacity, adapted to older adults and conducted following established safety guidelines.

Study Details

This study aims to evaluate the effects of a home intervention of individualized multicomponent physical exercise program (including strength, balance, flexibility, and mobility training) on functional health, physical capacity, and biological markers in centenarians. The intervention includes periodic monitoring and individualized exercise progression every three weeks.

Key Dates

First listed
Jul 23, 2026
Start date
Aug 13, 2026
Status verified
Aug 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • No Intervention: Control
    Participants assigned to the control group will receive usual care and will not undergo any specific intervention related to individualized multicomponent exerceise. They will continue doing their daily routine.
  • Experimental: Exercise
    Participants in this group will take part in a individualized multicomponent physical training program including exercises targeting strength, balance, and aerobic capacity, adapted to centenarians and conducted following established safety guidelines.

Primary Outcome Measure

Physical function assessed by Short Physical Performance Battery (SPPB) [ Time Frame: Baseline and 12-week follow-up ]

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