Effect of FPP on Cutaneous Barrier Integrity

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
University of Pittsburgh
Study ID
NCT07725835
Status
Not Yet Recruiting

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Conditions

  • Healthy Volunteers
  • Skin Barrier Dysfunction

Eligibility Criteria

Sex
ALL
Age
50 Years - 75 Years
Healthy Volunteers
Accepted

Interventions

  • Fermented Papaya Preparation (FPP) — DIETARY_SUPPLEMENT
    Immun'Age Fermented Papaya Preparation

Study Details

This pilot study will test how Fermented Papaya Preparation (FPP) impacts overall TEWL of areas that commonly display diminished barrier function, such as the skin from face, arms, and hands. Areas of diminished barrier function are defined as those not visible to the eye but identified as areas of high transepidermal water loss (TEWL) as measured by a non-invasive pen-like device. A TEWL value of 20 or higher at a location would be considered high TEWL. Participants will attend 5 visits over 20 weeks, with 12-weeks of FPP treatment, and 8-weeks of follow-up.

Key Dates

First listed
Jul 24, 2026
Start date
Sep 30, 2026
Status verified
Aug 2026
Primary completion
Apr 30, 2028
Completion
Jul 31, 2028

Study Design

Enrollment
30 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER

Arms

  • Experimental: Fermented Papaya Preparation
    Fermented Papaya Preparation Supplement

Primary Outcome Measure

Transepidermal Water Loss (TEWL) [ Time Frame: From enrollment to the end of FPP at 12 weeks. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
McGowan Institute for Regenerative MedicinePittsburghPennsylvania15219
Savita Khanna, PhD
[email protected]
412-624-5500
Scot King, DPT
[email protected]
Savita Khanna, PhD (PRINCIPAL_INVESTIGATOR)

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