Assessing Treatment With High-phenolic EVOO Supplements for Neurovascular Activity

Part of paid clinical trials in Augusta, Georgia.

Sponsor
Augusta University
Study ID
NCT07741773
Status
Not Yet Recruiting

Notify me when recruiting opens

Save your spot on the interest list for this study. We'll keep your details with this study so our team can follow up when recruiting opens.

Not yet recruiting

Add your contact details and location so we can keep your interest tied to this study.

Conditions

  • Mild Cognitive Impairment (MCI)

Eligibility Criteria

Sex
ALL
Age
50 Years - 70 Years
Healthy Volunteers
Not accepted

Interventions

  • EVOO-phenolics dietary supplement — DIETARY_SUPPLEMENT
    EVOO phenolic dietary supplement which is standardized to contain10 mg of EVOO total phenolics
  • Placebo — DIETARY_SUPPLEMENT
    Placebo

Study Details

The goal of this clinical trial is to determine whether the extra-virgin olive oil (EVOO) phenolic dietary supplement can improve memory function and modulate biomarkers among individuals with mild cognitive impairment (MCI). The main questions it aims to answer are: * Does dietary supplementation with EVOO phenolics improve cognitive function? * What would be the effect of the EVOO dietary supplement on other MCI-related biomarkers, including vascular function and biological pathways? Researchers will compare the EVOO dietary supplements with a placebo (a look-alike substance that contains no EVOO phenolics) Participants will: * Take EVOO dietary supplements or a placebo daily for 6 months * Visit the study site during the 6-month study for screening and testing.

Key Dates

First listed
Aug 3, 2026
Start date
Sep 1, 2026
Status verified
Jun 2026
Primary completion
Aug 31, 2028
Completion
Aug 31, 2028

Study Design

Enrollment
20 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Placebo Comparator: Placebo
    a look-alike tablet to the intervention that contains no EVOO-phenolics
  • Active Comparator: EVOO phenolics
    EVOO phenolics

Primary Outcome Measure

Cerebrovascular function [ Time Frame: At baseline and end of treatment (6 months) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Georgia prevention instituteAugustaGeorgia30912
Jacob Looney, MS
[email protected]
(706)-721-5483

Find similar trials in Augusta, GA

By research site
Georgia prevention institute· Augusta, GA

Related Studies