Gestational Response, Outcomes, and Weight After GLP-1 Use

Part of paid clinical trials in Kansas City, Kansas.

Sponsor
University of Kansas Medical Center
Study ID
NCT07743567
Status
Recruiting
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Conditions

  • Gestational Weight Gain
  • Obesity & Overweight
  • Pregnant Individuals

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 45 Years
Healthy Volunteers
Accepted

Study Details

The goal of this observational study is to learn if using GLP-1RA medications for weight loss before pregnancy influences gestational weight gain and pregnancy outcomes. The main aims of the study are to: * Compare gestational weight gain between women with preconception GLP-1RA exposure and those without exposure. * Compare obstetrical outcomes between women with preconception GLP-1RA exposure and those without exposure. Researchers will compare pregnant women with a history of GLP-1RA use to pregnant women who have not used a GLP-1RA to compare differences. Participants will be asked to complete questionnaires at multiple timepoints during and after pregnancy that ask questions about medication history, thoughts and feelings around food, etc.

Key Dates

First listed
Aug 4, 2026
Start date
Apr 13, 2026
Status verified
Jul 2026
Primary completion
Apr 30, 2028
Completion
Apr 30, 2028

Study Design

Enrollment
400 participants (estimated)

Arms

  • Arm: GLP-1RA users
    Participants with a history of GLP-1RA use.
  • Arm: GLP-1RA nonusers
    Participants who have never used a GLP-1RA medication.

Primary Outcome Measure

Gestational weight gain [ Time Frame: From the start of pregnancy to delivery. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Kansas Medical CenterKansas CityKansas66160
Molly Fain
[email protected]
913-588-5478
Johanna Finkle, MD (PRINCIPAL_INVESTIGATOR)

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