Contact Lenses to Slow Myopia Progression in Adults

Part of paid clinical trials in Berkeley, California.

Sponsor
University of California, Berkeley
Study ID
NCT07747311
Status
Not Yet Recruiting

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Conditions

  • Myopia
  • Myopia Progression

Eligibility Criteria

Sex
ALL
Age
18 Years - 30 Years
Healthy Volunteers
Not accepted

Interventions

  • Dual Focus Soft Contact Lens — DEVICE
    MiSight 1 day is a daily disposable dual-focus soft contact lens with two treatment zones and two distance vision correction zones arranged in concentric rings.
  • Single Vision Soft Contact Lens — DEVICE
    Proclear 1 day is a daily disposable single-vision soft contact lens that provides conventional correction of refractive error without myopia control treatment zones.

Study Details

Myopia (nearsightedness) can continue to worsen during young adulthood, increasing the risk of sight-threatening eye diseases later in life. Although dual-focus soft contacts (DFSC) lenses have been shown to slow myopia progression in children, their effectiveness in adults is not well understood. This study will compare DFSC lenses with standard single-vision soft contact (SVSC) lenses in myopic young adults aged 18 to 30 years. Participants will be randomly assigned to wear one of the two lens types for 24 months. The study will measure changes in axial length and cycloplegic refractive error to determine whether DFSC lenses slow myopia progression in young adults.

Key Dates

First listed
Aug 5, 2026
Start date
Sep 1, 2026
Status verified
Jul 2026
Primary completion
Sep 30, 2030
Completion
Sep 30, 2030

Study Design

Enrollment
152 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Treatment
    Participants will wear MiSight 1 day dual-focus soft contact lenses on a daily-wear basis for 24 months according to the study protocol.
  • Placebo Comparator: Control
    Participants will wear Proclear 1-day single-vision soft contact lenses on a daily wear basis for 24 months according to the study protocol.

Primary Outcome Measure

Cycloplegic Spherical Equivalent Refraction [ Time Frame: Baseline, 12 months, and 24 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University Of California, Berkeley Myopia Research GroupBerkeleyCalifornia94720
Ranjila Shyangbo
[email protected]
510-833-8625
[email protected]
Sarah Singh (PRINCIPAL_INVESTIGATOR)
Ranjila Shyangbo (SUB_INVESTIGATOR)
Karen Molina (SUB_INVESTIGATOR)

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By research site
University Of California, Berkeley Myopia Research Group· Berkeley, CA

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