One-level and Bi-level ESPB Application in Patients Undergoing Breast Surgery

Sponsor
Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Study ID
NCT07747623
Status
Not Yet Recruiting

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Conditions

  • Breast Surgery
  • Erector Spinae Plane Block
  • Multimodal Analgesia
  • Pain, Postoperative

Eligibility Criteria

Sex
FEMALE
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • One-level Erector Spinae Plane Block — PROCEDURE
    One-level Erector Spinae Plane Block will be performed unilaterally, under US guidance, before the surgical operation, and when the patient is placed in the lateral decubitus position. In applications, 30 ml of 0.25% bupivacaine will be injected at the T3 level.
  • Bi-level Erector Spinae Plane Block — PROCEDURE
    Bi-level Erector Spinae Plane Block will be performed unilaterally, under US guidance, before the surgical operation, and when the patient is placed in the lateral decubitus position. In applications, 15 ml of 0.25% bupivacaine at T2 level and 15 ml of 0.25% bupivacaine at T4 level will be injected.

Study Details

Acute pain after breast surgery can significantly reduce the quality of life for patients. If acute pain is not adequately treated, it can develop into chronic pain. Thoracic epidural analgesia, thoracic paravertebral block, erector spinae plane block, and serratus anterior plane block are frequently applied blocks. However, ESPB, being a fascial plane block, can yield inconsistent results regarding distribution and dermatomal area. In recent years, there has been an increase in publications applying ESPB from two levels to achieve wider distribution. As a result, this study aims to compare the analgesic efficacy of single-level (Thoracic 3) and two-level (Thoracic 2, Thoracic 4) ESPB applications.

Key Dates

First listed
Aug 5, 2026
Start date
Aug 14, 2026
Status verified
Jul 2026
Primary completion
Jan 10, 2027
Completion
Jan 20, 2027

Study Design

Enrollment
70 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: One-level Erector Spinae Plane Block
    After the linear ultrasound (US) probe will be placed 2-3 cm lateral to the T3 spinous process, 30 ml of 0.25% bupivacaine hydrochloride will be injected cauda-cranially into the interfacial space below the erector spinae muscle, above the transverse process.
  • Active Comparator: Bi-level Erector Spinae Plane Block
    After the linear ultrasound (US) probe will be placed 2-3 cm lateral to the T2 spinous process, 15 ml of 0.25% bupivacaine hydrochloride will be injected cauda-cranially into the interfacial space below the erector spinae muscle, above the transverse process. Next, the needle will be withdrawn till subcutaneously and the linear US probe will be placed 2-3 cm lateral to the T4 spinous process. Finally, 15 ml of 0.25% bupivacaine hydrochloride will be injected cranio-caudally into the interfacial space below the erector spinae muscle, above the transverse process.

Primary Outcome Measure

Pain scores [ Time Frame: 4th-hour after surgery ]

Central Contacts

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